Qin XiaoFeng, Zi Hao, Zeng XiaoJuan
College of Stomatology, Guangxi Medical University, Nanning 530021, China.
Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.
Heliyon. 2022 Sep 21;8(9):e10714. doi: 10.1016/j.heliyon.2022.e10714. eCollection 2022 Sep.
To investigate the burden of untreated dental caries in 204 countries and territories over 30 years.
Data of untreated dental caries from 1990 to 2019, including the incidence, prevalence, and years lived with disability, were extracted from the Global Burden of Disease 2019 database. Estimated annual percentage changes were calculated to assess the changes in the age-standardized incidence, prevalence, and years lived with disability rates.
Globally, in 2019, there were 3.09 billion (95% uncertainty interval [UI]: 2.76-3.39 billion) new cases of untreated dental caries in permanent teeth (48.00% increase), 2.03 billion (1.77-2.33) prevalent cases (46.07% increase), and 2.00 million (0.93-3.88) YLDs (45.64% increase), all since 1990. From 1990 to 2019, the age-standardized incidence rate (ASIR) of untreated dental caries in permanent teeth showed an upward trend (estimated annual percentage changes [EAPC] = 0.01), but age-standardized prevalence rate (ASPR) (EAPC = -0.13) and age-standardized YLD rate (ASYR) (EAPC = -0.13) decreased. There were 1.15 billion (0.79-1.52) new cases of untreated dental caries in deciduous teeth (11.74% increase), 0.52 billion (0.41-0.63) prevalent cases (5.89% increase), and 0.20 million (0.09-0.43) YLDs (6.03% increase), all since 1990. From 1990 to 2019, the ASIR of untreated dental caries in permanent teeth showed a stable trend (EAPC = 0), but the ASPR (EAPC = -0.15) and ASYR (EAPC = -0.14) decreased. The incidence of untreated dental caries peaked at the ages of 5-9 and 20-24 years, and the prevalence and years lived with disability at 1-4, 20-24, and 60-64 years.
Untreated dental caries remains a major global public health challenge, but demographic, sex, and regional differences in trends remain. Proactive intervention strategies, at both administrative and academic levels, based on dynamic changes, are needed.
调查204个国家和地区30年间未经治疗的龋齿负担。
从《2019年全球疾病负担》数据库中提取1990年至2019年未经治疗的龋齿数据，包括发病率、患病率和伤残调整生命年。计算估计的年百分比变化，以评估年龄标准化发病率、患病率和伤残调整生命年率的变化。
全球范围内，2019年恒牙新发未经治疗的龋齿病例有30.9亿例（95%不确定区间[UI]：27.6亿 - 33.9亿例）（增加48.00%），患病例数为20.3亿例（17.7亿 - 23.3亿例）（增加46.07%），伤残调整生命年为200万例（93万 - 388万例）（增加45.64%），均自1990年以来。1990年至2019年，恒牙未经治疗的龋齿年龄标准化发病率（ASIR）呈上升趋势（估计年百分比变化[EAPC]=0.01），但年龄标准化患病率（ASPR）（EAPC = -0.13）和年龄标准化伤残调整生命年率（ASYR）（EAPC = -0.13）下降。乳牙新发未经治疗的龋齿病例有11.5亿例（7.9亿 - 15.2亿例）（增加11.74%），患病例数为5.2亿例（4.1亿 - 6.3亿例）（增加5.89%），伤残调整生命年为20万例（9万 - 43万例）（增加6.03%），均自1990年以来。1990年至2019年，乳牙未经治疗的龋齿ASIR呈稳定趋势（EAPC = 0），但ASPR（EAPC = -0.15）和ASYR（EAPC = -0.14）下降。未经治疗的龋齿发病率在5 - 9岁和20 - 24岁达到峰值，患病率和伤残调整生命年在1 - 4岁、20 - 24岁和60 - 64岁达到峰值。
未经治疗的龋齿仍然是一项重大的全球公共卫生挑战，但在趋势方面存在人口统计学、性别和区域差异。需要基于动态变化在行政和学术层面采取积极的干预策略。
