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Detection of incompletely sialylated human chorionic gonadotropin by peanut agglutinin in choriocarcinoma.

作者信息

Nishimura R, Mizuochi T, Utsunomiya T, Ide K, Kobata A, Mochizuki M

出版信息

Jpn J Exp Med. 1985 Apr;55(2):75-8.

PMID:4046212
Abstract

Human chorionic gonadotropin (hCG) in normal pregnancy and hydatidiform mole did not bind to the peanut agglutinin (PNA)-Sepharose column, whereas significant amount of hCG in choriocarcinoma adsorbed to the column. Therefore, PNA-Sepharose affinity chromatography is an effective tool for the detection of desialylated hCG and may be useful also for the diagnosis of choriocarcinoma.

摘要

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