Detection of incompletely sialylated human chorionic gonadotropin by peanut agglutinin in choriocarcinoma.
作者信息
Nishimura R, Mizuochi T, Utsunomiya T, Ide K, Kobata A, Mochizuki M
出版信息
Jpn J Exp Med. 1985 Apr;55(2):75-8.
PMID:4046212
Abstract
Human chorionic gonadotropin (hCG) in normal pregnancy and hydatidiform mole did not bind to the peanut agglutinin (PNA)-Sepharose column, whereas significant amount of hCG in choriocarcinoma adsorbed to the column. Therefore, PNA-Sepharose affinity chromatography is an effective tool for the detection of desialylated hCG and may be useful also for the diagnosis of choriocarcinoma.
摘要
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