Manso Maria Isabel, Morais Henrique, Martins Ruben, Machado Mafalda, Martins Dos Santos Gildasio
General Surgery Department, Unidade Local de Saúde (ULS) Algarve, Faro, PRT.
General Surgery Department, Hospital de Loulé, Loulé, PRT.
Cureus. 2025 May 4;17(5):e83441. doi: 10.7759/cureus.83441. eCollection 2025 May.
Spontaneous rupture of hepatocellular carcinoma (HCC) is an uncommon and life-threatening condition that poses significant diagnostic and therapeutic challenges. This report describes the case of a 78-year-old man with no prior history of liver disease who presented with acute abdominal pain and hemoperitoneum. Imaging revealed a ruptured exophytic HCC lesion in hepatic segment II, which was confirmed during laparotomy. The patient underwent successful segment II resection following stabilization, and histopathological analysis confirmed a moderately differentiated HCC in a non-cirrhotic liver. The postoperative course was uneventful. This case highlights the importance of timely diagnosis, tailored management strategies, and multidisciplinary care in addressing the complexities of spontaneous HCC rupture, particularly in patients without underlying liver disease.
肝细胞癌（HCC）自发性破裂是一种罕见且危及生命的病症，带来了重大的诊断和治疗挑战。本报告描述了一名78岁男性病例，该患者既往无肝脏疾病史，因急性腹痛和腹腔积血就诊。影像学检查显示肝Ⅱ段有一外生性HCC破裂病灶，剖腹手术时得以证实。患者在病情稳定后成功接受了Ⅱ段切除术，组织病理学分析证实为非肝硬化肝脏中的中度分化HCC。术后过程顺利。该病例凸显了及时诊断、量身定制的管理策略以及多学科护理在应对自发性HCC破裂复杂性方面的重要性，尤其是在无潜在肝脏疾病的患者中。
