Suppr超能文献

非肝硬化肝脏自发性肝细胞癌破裂的手术治疗:一例报告

Surgical Management of a Spontaneous Hepatocellular Carcinoma Rupture in a Non-cirrhotic Liver: A Case Report.

作者信息

Manso Maria Isabel, Morais Henrique, Martins Ruben, Machado Mafalda, Martins Dos Santos Gildasio

机构信息

General Surgery Department, Unidade Local de Saúde (ULS) Algarve, Faro, PRT.

General Surgery Department, Hospital de Loulé, Loulé, PRT.

出版信息

Cureus. 2025 May 4;17(5):e83441. doi: 10.7759/cureus.83441. eCollection 2025 May.

Abstract

Spontaneous rupture of hepatocellular carcinoma (HCC) is an uncommon and life-threatening condition that poses significant diagnostic and therapeutic challenges. This report describes the case of a 78-year-old man with no prior history of liver disease who presented with acute abdominal pain and hemoperitoneum. Imaging revealed a ruptured exophytic HCC lesion in hepatic segment II, which was confirmed during laparotomy. The patient underwent successful segment II resection following stabilization, and histopathological analysis confirmed a moderately differentiated HCC in a non-cirrhotic liver. The postoperative course was uneventful. This case highlights the importance of timely diagnosis, tailored management strategies, and multidisciplinary care in addressing the complexities of spontaneous HCC rupture, particularly in patients without underlying liver disease.

摘要

肝细胞癌(HCC)自发性破裂是一种罕见且危及生命的病症,带来了重大的诊断和治疗挑战。本报告描述了一名78岁男性病例,该患者既往无肝脏疾病史,因急性腹痛和腹腔积血就诊。影像学检查显示肝Ⅱ段有一外生性HCC破裂病灶,剖腹手术时得以证实。患者在病情稳定后成功接受了Ⅱ段切除术,组织病理学分析证实为非肝硬化肝脏中的中度分化HCC。术后过程顺利。该病例凸显了及时诊断、量身定制的管理策略以及多学科护理在应对自发性HCC破裂复杂性方面的重要性,尤其是在无潜在肝脏疾病的患者中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8bc/12130909/8d3795e1cd24/cureus-0017-00000083441-i01.jpg

相似文献

1
Surgical Management of a Spontaneous Hepatocellular Carcinoma Rupture in a Non-cirrhotic Liver: A Case Report.
Cureus. 2025 May 4;17(5):e83441. doi: 10.7759/cureus.83441. eCollection 2025 May.
2
Spontaneous Rupture of Hepatocellular Carcinoma in a Young Patient with Fatal Outcome.
Case Rep Gastroenterol. 2018 Jan 17;12(1):19-26. doi: 10.1159/000486193. eCollection 2018 Jan-Apr.
3
Spontaneous rupture of hepatocellular carcinoma in children.
Afr J Paediatr Surg. 2010 Sep-Dec;7(3):188-90. doi: 10.4103/0189-6725.70424.
4
Unusual presentation of spontaneous ruptured hepatocellular carcinoma: Inguinal hernia.
Am J Emerg Med. 2024 Sep;83:161.e1-161.e3. doi: 10.1016/j.ajem.2024.07.029. Epub 2024 Jul 18.
5
Prognosis of patients with spontaneous rupture of hepatocellular carcinoma in cirrhosis.
Updates Surg. 2011 Mar;63(1):25-30. doi: 10.1007/s13304-010-0041-8. Epub 2011 Jan 22.
6
Spontaneous rupture of hepatocellular carcinoma: a case report and review of literature.
Int J Clin Pract Suppl. 2005 Apr(147):103-5. doi: 10.1111/j.1742-1241.2004.00257.x.
7
Recurrent umbilical varix rupture with hemoperitoneum: a case report and review of literature.
BMC Gastroenterol. 2022 Apr 1;22(1):160. doi: 10.1186/s12876-022-02167-3.
8
Successful multimodal management of a large hepatocellular carcinoma in a non-cirrhotic liver: a case report.
Acta Chir Belg. 2024 Jun;124(3):229-233. doi: 10.1080/00015458.2023.2234724. Epub 2023 Jul 23.
10
Emergency laparoscopic resection of spontaneous rupture of hepatocellular carcinoma: A case report.
Int J Surg Case Rep. 2020;66:104-106. doi: 10.1016/j.ijscr.2019.11.055. Epub 2019 Dec 3.

本文引用的文献

1
Spontaneously Ruptured Hepatocellular Carcinoma: Computed Tomography-Based Assessment.
Diagnostics (Basel). 2023 Mar 7;13(6):1021. doi: 10.3390/diagnostics13061021.
2
Ruptured Hepatocellular Carcinoma: Current Status of Research.
Front Oncol. 2022 Feb 17;12:848903. doi: 10.3389/fonc.2022.848903. eCollection 2022.
3
Hemoperitoneum caused by spontaneous rupture of hepatocellular carcinoma in noncirrhotic liver. A case report and systematic review.
Open Med (Wars). 2020 Aug 3;15(1):739-744. doi: 10.1515/med-2020-0202. eCollection 2020.
4
Acute hemoperitoneum after ruptured hepatocellular carcinoma: First Moroccan SCARE-compliant case report and literature review.
Int J Surg Case Rep. 2020;66:390-393. doi: 10.1016/j.ijscr.2019.12.038. Epub 2020 Jan 11.
5
Rupture of Hepatocellular Carcinoma: A Review of Literature.
J Clin Exp Hepatol. 2019 Mar-Apr;9(2):245-256. doi: 10.1016/j.jceh.2018.04.002. Epub 2018 Apr 26.
7
Spontaneous rupture of multifocal hepatocellular carcinoma: case report.
Int Med Case Rep J. 2015 Aug 17;8:165-7. doi: 10.2147/IMCRJ.S87746. eCollection 2015.
9
Treatment of spontaneous ruptured hepatocellular carcinoma: A single-center study.
Pak J Med Sci. 2014 May;30(3):472-6. doi: 10.12669/pjms.303.4001.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验