Hanaki Takehiko, Tanabe Hirotaka, Sakamoto Teruhisa, Ueki Masaru, Fujiwara Yoshiyuki
Department of Gastrointestinal and Pediatric Surgery, Tottori University Faculty of Medicine, Yonago, JPN.
Department of Medical Education, Tottori University Faculty of Medicine, Yonago, JPN.
Cureus. 2025 May 3;17(5):e83384. doi: 10.7759/cureus.83384. eCollection 2025 May.
Endoscopic ultrasonography-guided pancreatic duct drainage (EUS-PD) has become a valuable alternative to conventional retrograde approaches in treating chronic pancreatitis, particularly in cases where transpapillary access is technically unfeasible. Although generally considered safe and effective, EUS-PD can lead to rare but serious complications, such as stent migration, hemorrhage, and peritonitis. The surgical management of these adverse events remains inadequately documented in the clinical literature. We present the case of a 72-year-old man with a long-standing history of alcohol-related chronic pancreatitis and pancreatic diabetes who developed severe epigastric pain due to multiple intraductal pancreatic stones. Several attempts at endoscopic retrograde pancreatic lithotomy failed due to anatomical difficulties. EUS-PD was subsequently performed, and a covered self-expandable metal stent was placed transgastrically into the main pancreatic duct (MPD). Immediately after deployment, bleeding into the gastric lumen was observed. Contrast-enhanced computed tomography revealed stent migration from the MPD with active intraabdominal hemorrhage. The patient rapidly developed signs of peritonitis and hemodynamic instability, prompting an emergency laparotomy. Intraoperatively, the stent was found to have perforated the lesser and posterior gastric walls and was partially embedded in the pancreatic parenchyma. After removal of the stent, the gastric perforation was repaired, and hemostasis was achieved. A longitudinal pancreaticojejunostomy (Partington-Rochelle procedure) was performed to manage the injured and dilated pancreatic duct. The postoperative course was uneventful, with complete resolution of abdominal symptoms and no development of a pancreatic fistula. This case highlights the need for heightened awareness of potentially life-threatening EUS-PD-related complications. It also underscores the importance of timely surgical intervention and demonstrates that the Partington-Rochelle procedure can be a practical and effective option in emergency settings for managing ductal disruption caused by stent migration.
内镜超声引导下胰管引流术(EUS-PD)已成为治疗慢性胰腺炎的一种有价值的替代传统逆行方法,特别是在经乳头入路技术上不可行的情况下。尽管通常被认为是安全有效的,但EUS-PD可能导致罕见但严重的并发症,如支架移位、出血和腹膜炎。这些不良事件的外科处理在临床文献中仍记录不足。我们报告一例72岁男性患者,有长期酒精相关性慢性胰腺炎和胰腺糖尿病病史,因多发胰管内结石出现严重上腹痛。由于解剖学困难,多次内镜逆行胰管取石术尝试均失败。随后进行了EUS-PD,并经胃将一个覆膜自膨式金属支架置入主胰管(MPD)。支架置入后立即观察到胃腔内出血。增强CT显示支架从MPD移位并伴有腹腔内活动性出血。患者迅速出现腹膜炎体征和血流动力学不稳定,促使进行急诊剖腹手术。术中发现支架已穿透胃小弯和胃后壁并部分嵌入胰腺实质。取出支架后,修复胃穿孔并实现止血。进行了纵行胰空肠吻合术(Partington-Rochelle手术)以处理受损和扩张的胰管。术后过程顺利,腹部症状完全缓解,未发生胰瘘。该病例强调了对潜在危及生命的EUS-PD相关并发症提高认识的必要性。它还强调了及时手术干预的重要性,并表明Partington-Rochelle手术在紧急情况下可作为处理由支架移位引起的导管破裂的实用有效选择。