Mesgarzadeh Ali, Zandesh Amir, Sojoudi Hooman, Mesgarzadeh Ali Hossein, Esmaeili Farzad, Hajmohammadi Emran
Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
Student of Dentistry, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
J Dent Res Dent Clin Dent Prospects. 2025 Mar 31;19(1):40-45. doi: 10.34172/joddd.025.41648. eCollection 2025 Mar.
Little information is available about the effect of vitamin D on jaw bone density, and human studies about this entity are scarce. Vitamin D deficiency weakens bone regeneration and is responsible for many systemic diseases, such as chronic kidney disease, diabetes mellitus, etc.
Fifty candidates for dental implant treatment aged 20‒60 were randomly chosen at the Implantology Department of the Faculty of Dentistry, Tabriz University of Medical Sciences. Fifteen patients were male, and 35 were female, and they were examined for their vitamin D3 serum levels. All the patients had cone-beam computed tomography (CBCT) radiographic images. According to their vitamin D3 levels, they were split into three groups: deficient, insufficient, and sufficient, and the density of bone was evaluated using the mean calculated Hounsfield unit from the Planmeca Romexis software.
In the vitamin D3-deficient group, the mandibular bone of both males and females demonstrated lower bone densities; however, there was no significant correlation between bone density and vitamin D3 serum levels in either the maxilla or the mandible.
This study could not find a correlation between the serum levels of vitamin D3 and the bone density of the jaws. Further studies are necessary in this respect.
关于维生素D对颌骨密度的影响，现有信息较少，且针对该问题的人体研究稀缺。维生素D缺乏会削弱骨再生，并引发许多全身性疾病，如慢性肾病、糖尿病等。
在大不里士医科大学牙科学院种植科随机选取50名年龄在20至60岁之间的牙种植治疗候选人。其中15名患者为男性，35名患者为女性，对他们进行了维生素D3血清水平检测。所有患者均有锥形束计算机断层扫描（CBCT）影像学图像。根据他们的维生素D3水平，将其分为三组：缺乏组、不足组和充足组，并使用Planmeca Romexis软件计算的平均亨氏单位来评估骨密度。
在维生素D3缺乏组中，男性和女性的下颌骨骨密度均较低；然而，在上颌骨或下颌骨中，骨密度与维生素D3血清水平之间均无显著相关性。
本研究未发现维生素D3血清水平与颌骨骨密度之间存在相关性。在这方面需要进一步研究。
