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纳米机器人和纳米载体在癌症治疗中的治疗应用。

Therapeutic applications of nanobots and nanocarriers in cancer treatment.

作者信息

Khan Zaitoon, Khan Nimra, Geetha Mithra, Veettil Reyhanath Pilakka, Kasote Deepak Mahadev, Hasan Anwarul, Sadasivuni Kishor Kumar

机构信息

Center for Advanced Materials, Qatar University, Doha, Qatar.

Agricultural Research Station, Qatar University, Doha, Qatar.

出版信息

Anal Sci. 2025 Jun 4. doi: 10.1007/s44211-025-00799-5.

Abstract

Cancer remains a pressing global health concern, burdening individuals, families, and healthcare systems worldwide, mainly because of the limited availability of therapeutic options. These days, nanotechnology is revolutionizing cancer research by offering promising drug delivery systems. Among these, nanobots and nanocarriers are key nanotechnology components, offering groundbreaking strategies in cancer therapy by delivering drugs, enhancing diagnostics, and preventing diseases at molecular levels. Nanobots and nanocarriers, engineered at sizes ranging from 1 to 100 nm, demonstrate biocompatibility with cellular systems, offer precise drug delivery, and reduce side effects compared to conventional therapies such as chemotherapy and surgery. Research efforts now focus on transitioning nanobots and nanocarriers from laboratories to clinics, aiming for precision medicine, targeted drug delivery, enhanced therapy efficacy, and minimal side effects. This review aims to highlight the potential of nanobots and nanocarriers in cancer treatment and provide insights into their role in paving the way for clinical applications and improving outcomes in cancer therapy.

摘要

癌症仍然是一个紧迫的全球健康问题,给世界各地的个人、家庭和医疗保健系统带来负担,主要原因是治疗选择有限。如今,纳米技术通过提供有前景的药物递送系统,正在彻底改变癌症研究。其中,纳米机器人和纳米载体是关键的纳米技术组件,通过在分子水平上递送药物、增强诊断和预防疾病,为癌症治疗提供了开创性的策略。纳米机器人和纳米载体的尺寸设计在1到100纳米之间,与细胞系统具有生物相容性,能够实现精确的药物递送,与化疗和手术等传统疗法相比,副作用更小。目前的研究工作集中在将纳米机器人和纳米载体从实验室转化到临床,目标是实现精准医学、靶向药物递送、提高治疗效果以及将副作用降至最低。本综述旨在强调纳米机器人和纳米载体在癌症治疗中的潜力,并深入探讨它们在为临床应用铺平道路以及改善癌症治疗结果方面所起的作用。

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