Fonte Ana Luiza Fassizoli da, Costa Guilherme Jorge, Fonte Neto Adilis Stepple da, Pinto Rodrigo Alves, Mello Maria Júlia Gonçalves de
Instituto de Medicina Integral Professor Fernando Figueira, Department of Radiotherapy - Recife (PE), Brazil.
Hospital de Câncer de Pernambuco, Department of Education and Research - Recife (PE), Brazil.
Rev Bras Epidemiol. 2025 Jun 2;28:e250031. doi: 10.1590/1980-549720250031. eCollection 2025.
OBJECTIVE: This study compared treatments and outcomes between patients younger than 70 years and those aged 70 years or older (elderly) with laryngeal cancer (LC). METHODS: Data were collected from Brazilian hospital records between 2000 and 2017. RESULTS: A total of 38,978 patients were analysed, of whom 8,803 (22.6%) were ≥70 years old. Elderly patients were more frequently diagnosed at early stages (39.3% vs. 28.9%; p<0.001). However, these patients were 15% less likely to undergo surgery, 46% less likely to receive chemotherapy, and 33% less likely to receive combined treatments. In addition, elderly patients were 35% more likely to receive supportive care only. CONCLUSIONS: Despite early diagnosis, elderly patients received fewer oncological treatments and more palliative care.
目的：本研究比较了70岁以下和70岁及以上（老年）喉癌（LC）患者的治疗方法和治疗结果。 方法：数据收集自2000年至2017年巴西医院的记录。 结果：共分析了38978例患者，其中8803例（22.6%）年龄≥70岁。老年患者更常被诊断为早期（39.3%对28.9%；p<0.001）。然而，这些患者接受手术的可能性降低了15%，接受化疗的可能性降低了46%，接受联合治疗的可能性降低了33%。此外，老年患者仅接受支持性治疗的可能性增加了35%。 结论：尽管早期诊断，但老年患者接受的肿瘤治疗较少，而姑息治疗较多。
Rev Bras Epidemiol. 2025-6-2
J Cancer Res Clin Oncol. 2017-8
Laryngoscope. 2018-7
Arch Otolaryngol Head Neck Surg. 2011-10
J Am Coll Surg. 2001-6
Acta Otorrinolaringol Esp. 2011
Cancer Epidemiol. 2023-8
Zotero 插件