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本文引用的文献

1
Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.2022 年全球癌症统计数据:全球 185 个国家和地区 36 种癌症的发病率和死亡率全球估计数。
CA Cancer J Clin. 2024 May-Jun;74(3):229-263. doi: 10.3322/caac.21834. Epub 2024 Apr 4.
2
Epidemiology of laryngeal cancer in Brazil: Historical data from 2000 to 2019.巴西喉癌的流行病学:2000 年至 2019 年的历史数据。
Cancer Epidemiol. 2023 Aug;85:102397. doi: 10.1016/j.canep.2023.102397. Epub 2023 Jun 14.
3
Defining Undertreatment and Overtreatment in Older Adults With Cancer: A Scoping Literature Review.定义老年癌症患者的治疗不足和过度治疗:文献范围综述。
J Clin Oncol. 2020 Aug 1;38(22):2558-2569. doi: 10.1200/JCO.19.02809. Epub 2020 Apr 6.
4
Use of Larynx-Preservation Strategies in the Treatment of Laryngeal Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update.喉癌保喉治疗策略的应用:美国临床肿瘤学会临床实践指南更新。
J Clin Oncol. 2018 Apr 10;36(11):1143-1169. doi: 10.1200/JCO.2017.75.7385. Epub 2017 Nov 27.
5
Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients.头颈部癌化疗的荟萃分析(MACH-NC):93项随机试验及17346例患者的最新情况
Radiother Oncol. 2009 Jul;92(1):4-14. doi: 10.1016/j.radonc.2009.04.014. Epub 2009 May 14.

巴西老年喉癌患者接受治疗不足的倾向更高。

Higher tendency of undertreatment in older patients with laryngeal cancer in Brazil.

作者信息

Fonte Ana Luiza Fassizoli da, Costa Guilherme Jorge, Fonte Neto Adilis Stepple da, Pinto Rodrigo Alves, Mello Maria Júlia Gonçalves de

机构信息

Instituto de Medicina Integral Professor Fernando Figueira, Department of Radiotherapy - Recife (PE), Brazil.

Hospital de Câncer de Pernambuco, Department of Education and Research - Recife (PE), Brazil.

出版信息

Rev Bras Epidemiol. 2025 Jun 2;28:e250031. doi: 10.1590/1980-549720250031. eCollection 2025.

DOI:10.1590/1980-549720250031
PMID:40465879
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12129238/
Abstract

OBJECTIVE

This study compared treatments and outcomes between patients younger than 70 years and those aged 70 years or older (elderly) with laryngeal cancer (LC).

METHODS

Data were collected from Brazilian hospital records between 2000 and 2017.

RESULTS

A total of 38,978 patients were analysed, of whom 8,803 (22.6%) were ≥70 years old. Elderly patients were more frequently diagnosed at early stages (39.3% vs. 28.9%; p<0.001). However, these patients were 15% less likely to undergo surgery, 46% less likely to receive chemotherapy, and 33% less likely to receive combined treatments. In addition, elderly patients were 35% more likely to receive supportive care only.

CONCLUSIONS

Despite early diagnosis, elderly patients received fewer oncological treatments and more palliative care.

摘要

目的

本研究比较了70岁以下和70岁及以上(老年)喉癌(LC)患者的治疗方法和治疗结果。

方法

数据收集自2000年至2017年巴西医院的记录。

结果

共分析了38978例患者,其中8803例(22.6%)年龄≥70岁。老年患者更常被诊断为早期(39.3%对28.9%;p<0.001)。然而,这些患者接受手术的可能性降低了15%,接受化疗的可能性降低了46%,接受联合治疗的可能性降低了33%。此外,老年患者仅接受支持性治疗的可能性增加了35%。

结论

尽管早期诊断,但老年患者接受的肿瘤治疗较少,而姑息治疗较多。