Costa Guilherme Jorge, Veras Santos Ana Luiza Ribeiro, Mendes de Sales Júlia Nathaly Cavalcanti, Bernhoeft Bruna Freire, Sales Letícia Telles, Oliveira Lima Jurema Telles de, de Mello Maria Júlia Gonçalves, Thuler Luiz Claudio Santos
Department of Pneumology, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Pernambuco, Brazil; Stricto sensu Postgraduate Program, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Pernambuco, Brazil.
Undergraduate Medical Students, Faculdade Pernambucana de Saúde, Recife, Pernambuco, Brazil.
Cancer Epidemiol. 2025 Feb;94:102741. doi: 10.1016/j.canep.2024.102741. Epub 2025 Jan 4.
Cancer has become a public health problem worldwide, affecting individuals of different age groups, including children, young adults and older patients.
To determine the clinical profile, staging and standard of oncological treatment of the 10 most frequent primary sites of cancer in young patients (< 60 years) vs older patients (≥ 60 years old) diagnosed between 2000 and 2019 in Brazil.
This cross-sectional study used data from the secondary database of the Hospital Cancer Registry, available on the web www.inca.org.br. Patients with cancer who were older than 18 years were included. Patients with non-melanoma skin cancer and with incomplete data on primary site and staging were excluded.
The database had data from 1,891,912 eligible patients, of which 1,461,080 (77.2 %) corresponded to the ten leading cancer types which were to be evaluated in this study. Cancers of the breast, prostate, cervix, lung, colon, stomach, rectum, oesophagus, thyroid and larynx were the 10 most frequent cancer types identified. The mean of age of patients was 58.8 ± 14.2 years and most of them were female (59.8 %). Those in the older group were more commonly reported (50.8 %) and this group included more former or current smokers (48.4 % vs 40.8 %, p < 0.001). Young patients received more all-oncological treatment: surgery (53.2 % vs 41.1 %, p < 0.001), radiotherapy (47.3 % vs 46.3 %, p < 0.001) and chemotherapy (53.6 % vs 39.3 %, p < 0.001) than older patients.
Evaluating cancer patients by age group may enhance cancer surveillance, redirecting control strategies and prioritising patients with more common primary site types.
癌症已成为全球公共卫生问题，影响着不同年龄组的个体，包括儿童、年轻人和老年患者。
确定2000年至2019年在巴西诊断出的年轻患者（<60岁）与老年患者（≥60岁）中10种最常见癌症原发部位的临床特征、分期和肿瘤治疗标准。
本横断面研究使用了可从网站www.inca.org.br获取的医院癌症登记处二级数据库中的数据。纳入年龄超过18岁的癌症患者。排除非黑色素瘤皮肤癌患者以及原发部位和分期数据不完整的患者。
该数据库包含来自1,891,912名符合条件患者的数据，其中1,461,080名（77.2%）对应于本研究中要评估的十种主要癌症类型。乳腺癌、前列腺癌、宫颈癌、肺癌、结肠癌、胃癌、直肠癌、食管癌、甲状腺癌和喉癌是确定的10种最常见癌症类型。患者的平均年龄为58.8±14.2岁，其中大多数为女性（59.8%）。老年组患者报告更为常见（50.8%），且该组中曾经或现在吸烟者更多（48.4%对40.8%，p<0.001）。年轻患者接受的所有肿瘤治疗更多：手术（53.2%对41.1%，p<0.001）、放疗（47.3%对46.3%，p<0.001）和化疗（53.6%对39.3%，p<0.001）。
按年龄组评估癌症患者可能会加强癌症监测，重新调整控制策略并优先考虑原发部位类型更常见的患者。
