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量化镁在人类死亡率/发病率与水硬度之间相互关系中的作用。

Quantifying the role of magnesium in the interrelationship between human mortality/morbidity and water hardness.

作者信息

Marier J R, Neri L C

出版信息

Magnesium. 1985;4(2-3):53-9.

PMID:4046646
Abstract

An attempt has been made to quantify the effect of waterborne magnesium on human mortality/morbidity, based on epidemiological and clinical observations reported in several regions of the modern-day world. A consistent pattern has emerged, indicative of a global phenomenon, which illustrates the importance of waterborne magnesium in protecting against cardiovascular trauma and other ailments. These findings attest to the inadequate metabolic magnesium status among modern-day humans, especially those who reside in ultra-soft-water localities.

摘要

基于现代世界多个地区报告的流行病学和临床观察结果,人们已尝试对水中镁对人类死亡率/发病率的影响进行量化。一种一致的模式已经出现,表明这是一种全球现象,这说明了水中镁在预防心血管损伤和其他疾病方面的重要性。这些发现证明了现代人类,尤其是居住在极软水地区的人群,其代谢镁状态不足。

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1
Quantifying the role of magnesium in the interrelationship between human mortality/morbidity and water hardness.量化镁在人类死亡率/发病率与水硬度之间相互关系中的作用。
Magnesium. 1985;4(2-3):53-9.
2
[Drinking water hardness and chronic degenerative diseases. II. Cardiovascular diseases].[饮用水硬度与慢性退行性疾病。II. 心血管疾病]
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[Epidemiological correlation between the hardness of the drinking water and cardiovascular mortality].[饮用水硬度与心血管疾病死亡率之间的流行病学关联]
Ann Sanita Pubblica. 1971 Jan-Feb;32(1):45-60.
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[The hardness of drinking water and cardiovascular diseases].[饮用水硬度与心血管疾病]
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Content of magnesium in drinking water and deaths from ischaemic heart disease in white South Africans.南非白人饮用水中的镁含量与缺血性心脏病死亡率
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Development of the 'Water Story': some recent Canadian studies.《水的故事》的发展:加拿大近期的一些研究
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引用本文的文献

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Short-term magnesium deficiency downregulates telomerase, upregulates neutral sphingomyelinase and induces oxidative DNA damage in cardiovascular tissues: relevance to atherogenesis, cardiovascular diseases and aging.短期镁缺乏会下调端粒酶、上调中性鞘磷脂酶,并在心血管组织中诱导氧化性DNA损伤:与动脉粥样硬化、心血管疾病及衰老的相关性。
Int J Clin Exp Med. 2014 Mar 15;7(3):497-514. eCollection 2014.
2
Short-term Mg deficiency upregulates protein kinase C isoforms in cardiovascular tissues and cells; relation to NF-kB, cytokines, ceramide salvage sphingolipid pathway and PKC-zeta: hypothesis and review.短期镁缺乏上调心血管组织和细胞中的蛋白激酶C亚型;与核因子-κB、细胞因子、神经酰胺挽救鞘脂途径和蛋白激酶C-ζ的关系:假说与综述
Int J Clin Exp Med. 2014 Jan 15;7(1):1-21. eCollection 2014.
3
Magnesium deficiency upregulates sphingomyelinases in cardiovascular tissues and cells: cross-talk among proto-oncogenes, Mg(2+), NF-κB and ceramide and their potential relationships to resistant hypertension, atherogenesis and cardiac failure.镁缺乏上调心血管组织和细胞中的鞘磷脂酶:原癌基因、Mg(2+)、核因子κB和神经酰胺之间的相互作用及其与难治性高血压、动脉粥样硬化形成和心力衰竭的潜在关系。
Int J Clin Exp Med. 2013 Oct 25;6(10):861-79. eCollection 2013.
4
Potential health impacts of hard water.硬水对健康的潜在影响。
Int J Prev Med. 2013 Aug;4(8):866-75.
5
Mg deficiency results in modulation of serum lipids, glutathione, and NO synthase isozyme activation in cardiovascular tissues: relevance to de novo synthesis of ceramide, serum Mg and atherogenesis.镁缺乏导致心血管组织中血清脂质、谷胱甘肽的调节以及一氧化氮合酶同工酶激活:与神经酰胺的从头合成、血清镁和动脉粥样硬化的相关性。
Int J Clin Exp Med. 2011;4(2):103-18. Epub 2011 Apr 5.
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Short-term magnesium deficiency upregulates sphingomyelin synthase and p53 in cardiovascular tissues and cells: relevance to the de novo synthesis of ceramide.短期镁缺乏上调心血管组织和细胞中的鞘磷脂合酶和 p53:与神经酰胺的从头合成有关。
Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H2046-55. doi: 10.1152/ajpheart.00671.2010. Epub 2010 Oct 8.
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Iron accumulation in tissues of magnesium-deficient rats with dietary iron overload.饮食中铁过载的缺镁大鼠组织中的铁蓄积。
Biol Trace Elem Res. 1996 Feb;51(2):177-97. doi: 10.1007/BF02785437.
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