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[噪声应激后适应阶段过程的电生理研究]

[Electrophysiologic studies on the course of the adaptation phase following noise stress].

作者信息

von Wedel H, Dum N, Walger M

出版信息

Laryngol Rhinol Otol (Stuttg). 1985 Aug;64(8):436-40.

PMID:4046695
Abstract

It was the aim of this study to settle the problem whether the post-stimulatory pattern of the extent of excitation (amplitude, latency) registered with the cortical evoked potentials can be verified in the recovery phase via leads from the brain stem region and cochlea. In this context electrophysiological measurements with human and animal material were performed. After a five-minute stimulation with a wide-band noise of various intensity we examined in the post-stimulation phase the specific stimulus pattern of the evoked potentials during an interval of 5 minutes with a resolution of 5 sec. We determined the change in response patterns of evoked potentials. Finally, the relevance of the results with regard to various nuclei of the auditory pathway is compared with corresponding electrophysiological measurements of the cochlear microphonics potentials, the VIII nerve compound action potential, and evoked potentials of different units of the brain stem and brain.

摘要

本研究的目的是解决以下问题

通过脑干区域和耳蜗的导联,能否在恢复阶段验证皮层诱发电位记录的刺激后兴奋程度(幅度、潜伏期)模式。在此背景下,对人和动物材料进行了电生理测量。在用不同强度的宽带噪声刺激五分钟后,我们在刺激后阶段,以5秒的分辨率,在5分钟的间隔内检查诱发电位的特定刺激模式。我们确定了诱发电位反应模式的变化。最后,将关于听觉通路各个核团的结果相关性与耳蜗微音器电位、第八对脑神经复合动作电位以及脑干和大脑不同单元的诱发电位的相应电生理测量结果进行比较。

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