Breiman Robert F, Osoro Eric, Reithinger Richard, Wang David, Diamond Michael, Van Voorhis Wesley C, Wasserheit Judith N, Rabinowitz Peter MacGarr, Mboup Souleymane, Hemingway-Foday Jennifer J, de Oliveira Tulio, Boon Adrianus C M, Schieffelin J S, Sempowski Gregory D, Moody M Anthony, Vasilakis Nikos, Hanley Kathryn A, Nasimiyu Carolyne, Situma Silvia, Ngere Isaac, Kyobe Bosa Henry, Nyakarahuka Luke, Bakamutumaho Barnabas, Woodson Sara E, Njenga M Kariuki
Rollins School for Public Health, Emory University, Atlanta, Georgia, USA.
Center for Research in Emerging Infectious Diseases-East and Central Africa, Washington State University, Nairobi, Kenya.
BMJ Glob Health. 2025 Jun 4;10(6):e018297. doi: 10.1136/bmjgh-2024-018297.
An important outcome of the devastating 2014 West African Ebola virus disease outbreak and the 2020 COVID-19 pandemic has been the growing promotion of conducting research during outbreaks of emerging infectious diseases (EIDs) as a valuable and acceptable process of acquiring knowledge to enhance our ability to better prevent and control these diseases in the future. Recognising the unique opportunity during outbreaks to leverage increases in cases over a short time interval and in a circumscribed area, we articulate a systematic process of conducting EID outbreak response research, highlighting knowledge gaps that should be prioritised, and measures that can be applied to mitigate numerous barriers commonly experienced during such times. We also highlight ethical considerations that must be addressed to minimise practices that continue to erode global confidence in sharing specimens and data.
2014年西非埃博拉病毒病疫情的惨痛爆发以及2020年的新冠疫情带来的一个重要成果是，越来越多的人提倡在新发传染病（EID）爆发期间开展研究，将其视为获取知识以提升我们未来更好地预防和控制这些疾病能力的一个有价值且可接受的过程。认识到疫情期间在短时间间隔和限定区域内利用病例增加这一独特机会，我们阐述了开展新发传染病疫情应对研究的系统流程，强调了应优先考虑的知识空白以及可用于减轻此类时期常见的诸多障碍的措施。我们还强调了必须解决的伦理考量，以尽量减少那些继续侵蚀全球对标本和数据共享信心的做法。
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