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2021 - 2024年沙特阿拉伯一家三级医疗中心关于2岁以下儿童新冠疫情后细支气管炎负担的经验

Burden of bronchiolitis post-COVID-19 pandemic in children less than 2 years old in 2021-2024: experience from a tertiary center in Saudi Arabia.

作者信息

Alrashed Rawan, Almeshawi Ibtihal, Alshammari Asmaa, Alhamoud Wateen, AlShathri Reem, Alotaibi Aliyah, Saja Danyah, Algoraini Yara

机构信息

Pediatric Emergency Department, King Fahad Medical City, Riyadh, Saudi Arabia.

General Pediatric Medicine Department, King Fahad Medical City, Riyadh, Saudi Arabia.

出版信息

BMC Pediatr. 2025 Jun 4;25(1):453. doi: 10.1186/s12887-025-05801-7.

Abstract

BACKGROUND

Bronchiolitis, a common lower respiratory tract infection in children under 2, is primarily caused by respiratory syncytial virus (RSV). During the coronavirus disease (COVID-19) pandemic, respiratory infections initially decreased due to non-pharmaceutical interventions; however, patients with bronchiolitis have surged in the post-pandemic period. This study examined the burden and severity of bronchiolitis in the post-COVID era in a tertiary center in Saudi Arabia.

METHODS

This retrospective review was conducted on pediatric patients aged < 2 years who were diagnosed with bronchiolitis at a tertiary hospital in Riyadh between September 2021 and March 2024. The collected data included demographics, comorbidities, viral polymerase chain reaction results, clinical management, disposition, and outcomes. Statistical analysis was performed using SPSS, with statistical significance at p < 0.05.

RESULTS

Out of 482 patients, 56% were male, with a mean age of 6.37 months. RSV was the most common virus (53.79%) among the 132 tested patients. Oxygen therapy was administered to 93.15% of patients, with only 4.36% requiring high-flow nasal cannula and 0.41% requiring intubation. Pediatric Intensive Care Unit admission was necessary for 5.6%, with most managed with non-invasive support. Complications were infrequent; only 4.77% developed pneumonia.

CONCLUSIONS

The findings reflect a significant increase in patients with bronchiolitis post-COVID, consistent with the global trends. Despite this increase, most patients required minimal intervention, aligning with pre-pandemic management practices. This study highlighted the post-pandemic resurgence of bronchiolitis. While the caseload has increased, outcomes remain favorable, reinforcing the importance of supportive care and judicious resource allocation during the bronchiolitis season.

摘要

背景

细支气管炎是2岁以下儿童常见的下呼吸道感染,主要由呼吸道合胞病毒(RSV)引起。在冠状病毒病(COVID-19)大流行期间,由于非药物干预措施,呼吸道感染最初有所减少;然而,在大流行后时期,细支气管炎患者数量激增。本研究调查了沙特阿拉伯一家三级中心在COVID后时代细支气管炎的负担和严重程度。

方法

对2021年9月至2024年3月期间在利雅得一家三级医院被诊断为细支气管炎的2岁以下儿科患者进行了这项回顾性研究。收集的数据包括人口统计学信息、合并症、病毒聚合酶链反应结果、临床管理、处置情况和结局。使用SPSS进行统计分析,p < 0.05具有统计学意义。

结果

在482例患者中,56%为男性,平均年龄为6.37个月。在132例接受检测的患者中,RSV是最常见的病毒(53.79%)。93.15%的患者接受了氧疗,只有4.36%的患者需要高流量鼻导管吸氧,0.41%的患者需要插管。5.6%的患者需要入住儿科重症监护病房(PICU),大多数患者通过无创支持进行管理。并发症很少见;只有4.77%的患者发生了肺炎。

结论

研究结果反映出COVID后细支气管炎患者数量显著增加,这与全球趋势一致。尽管患者数量有所增加,但大多数患者只需进行最小程度的干预,这与大流行前的管理做法一致。本研究突出了细支气管炎在大流行后的复发情况。虽然病例数量有所增加,但结局仍然良好,这强化了在细支气管炎季节提供支持性护理和合理分配资源的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f81/12135589/78ed86c23fdb/12887_2025_5801_Fig1_HTML.jpg

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