全髋关节置换术后深静脉血栓形成的危险因素：一项荟萃分析。

Risk factors for deep venous thrombosis following total hip arthroplasty: a meta-analysis.

作者信息

Wang Tao, Zhang Qi, Hou Zhiyong

机构信息

Department of Lower Limb Trauma, Beijing Jishuitan Hospital, Guizhou Hospital, Baiyun District, Guiyang, Guizhou, China.

Department of Anesthesiology, Children's hospital of Hebei Province, Shijiazhuang, Hebei, P.R. China.

出版信息

Thromb J. 2025 Jun 4;23(1):58. doi: 10.1186/s12959-025-00744-6.

DOI:10.1186/s12959-025-00744-6

PMID:40468359

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12135298/

Abstract

OBJECTIVE

We aim to investigate the predictors of deep venous thrombosis (DVT) following total hip arthroplasty (THA) by meta-analysis.

METHODS

We collected potential indicators of DVT from related literature in the English databases of PubMed, Embase, and the Cochrane Library. We used RevMan 5.3 and STATA 12.0 to analyze potential indicators of DVT after THA.

RESULTS

Finally, there were 6 English articles included in our study, and the rate of DVT after THA was 18.9% (270 of 1428 patients). Our findings indicated that advanced age [<0.00001, OR = 4.51, 95% CI (2.91, 6.10)], female patients [ = 0.008, OR = 0.65, 95% CI (0.47, 0.89)], body mass index [ = 0.01, OR = 0.76, 95% CI (0.15, 1.37)], diabetes [ = 0.01, OR = 1.85, 95% CI (1.14, 3.01)], malignancy [ = 0.001, OR = 2.54, 95% CI (1.46, 4.41)], uncemented prosthesis[ = 0.0003, OR = 0.22, 95% CI (0.10, 0.50)], and longer operation time [<0.00001, OR = 33.50, 95% CI (23.59, 43.41)] were predictors for DVT following THA.

CONCLUSIONS

Many factors were found to be associated with DVT after THA. We provided references when we met the above characteristics of patients.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1186/s12959-025-00744-6.

摘要

目的

通过荟萃分析探讨全髋关节置换术（THA）后深静脉血栓形成（DVT）的预测因素。

方法

我们从PubMed、Embase和Cochrane图书馆的英文数据库中的相关文献中收集DVT的潜在指标。我们使用RevMan 5.3和STATA 12.0分析THA后DVT的潜在指标。

结果

最终，我们的研究纳入了6篇英文文章，THA后DVT的发生率为18.9%（1428例患者中的270例）。我们的研究结果表明，高龄[<0.00001，OR = 4.51，95%CI（2.91, 6.10）]、女性患者[= 0.008，OR = 0.65，95%CI（0.47, 0.89）]、体重指数[= 0.01，OR = 0.76，95%CI（0.15, 1.37）]、糖尿病[= 0.01，OR = 1.85，95%CI（1.14, 3.01）]、恶性肿瘤[= 0.001，OR = 2.54，95%CI（1.46, 4.41）]、非骨水泥假体[= 0.0003，OR = 0.22，95%CI（0.10, 0.50）]以及较长的手术时间[<0.00001，OR = 33.50，95%CI（23.59, 43.41）]是THA后DVT的预测因素。