Trotter Brittany, Hunfalvay Melissa, Murray Nicholas P, Mathews Greg C, Carrick Frederick Robert
East Carolina University, Department of Kinesiology, Greenville, NC, United States.
RightEye LLC, Bethesda, MD, United States.
Front Hum Neurosci. 2025 May 21;19:1556451. doi: 10.3389/fnhum.2025.1556451. eCollection 2025.
The purpose of this study was to assess the validity of six computerized eye-tracking tests against a clinician-administered oculomotor exam.
A total of 53 participants completed the horizontal random saccade (HRS), circular smooth pursuit (CSP), horizontal smooth pursuit (HSP), vertical smooth pursuit (VSP), horizontal saccade (HS), and vertical saccade (VS) oculomotor tests on the computerized system. A board-certified neurologist with 16 years of experience also conducted an oculomotor examination to mirror eye movement patterns.
Data analysis included a series of single-block logistic regressions to examine the scoring of the six eye-tracking tests (RightEye, LLC) to predict clinician-rated eye movement classifications (i.e., normal or abnormal). The computerized battery demonstrated concurrent validity for each of the six oculomotor tests as they significantly predicted the neurologist's classification. The sensitivity and specificity of the six eye-tracking tests ranged from 70.4 to 93.5% and from 84.6 to 90.5%, respectively. The diagnostic accuracy of the computerized tests ranged from good (78.8%) to excellent (92.3%). The area under the curve (AUC) analysis for the eye-tracking tests yielded values ranging from 0.734 (VSs) to 0.921 (HRSs).
The results suggest that each of the six computerized eye-tracking tests accurately distinguished between normal and abnormal oculomotor movements.
本研究旨在评估六项计算机化眼动追踪测试相对于临床医生实施的动眼神经检查的有效性。
共有53名参与者在计算机系统上完成了水平随机扫视（HRS）、圆周平滑追踪（CSP）、水平平滑追踪（HSP）、垂直平滑追踪（VSP）、水平扫视（HS）和垂直扫视（VS）动眼神经测试。一名拥有16年经验的获得委员会认证的神经科医生也进行了动眼神经检查以反映眼动模式。
数据分析包括一系列单组逻辑回归，以检查六项眼动追踪测试（右眼，LLC）的评分，以预测临床医生评定的眼动分类（即正常或异常）。计算机化测试组显示六项动眼神经测试中的每一项都具有同时效度，因为它们显著预测了神经科医生的分类。六项眼动追踪测试的敏感性和特异性分别为70.4%至93.5%和84.6%至90.5%。计算机化测试的诊断准确性从良好（78.8%）到优秀（92.3%）不等。眼动追踪测试的曲线下面积（AUC）分析得出的值范围为0.734（VSs）至0.921（HRSs）。
结果表明，六项计算机化眼动追踪测试中的每一项都能准确区分正常和异常的动眼神经运动。
