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慢性硬膜下血肿:墨西哥神经外科住院医师培训项目中的临床经验及复发风险因素

Chronic subdural hematoma: Clinical experience and recurrence risk factors in a Mexican neurosurgery residency training program.

作者信息

Ponce-Ayala Aurelio, Gutiérrez-Baños José de Jesús, Mendizabal-Guerra Rafael, Rodriguez-Pereira Mauricio Ivan, Carrizales-Rodriguez Juan

机构信息

Department of Neurosurgery and Spine Surgery, Centennial Hospital, Miguel Hidalgo, Aguascalientes, Mexico.

Department of Endovascular Neurosurgery, October 1st Regional Hospital, ISSSTE, Mexico City, Mexico.

出版信息

Surg Neurol Int. 2025 May 16;16:181. doi: 10.25259/SNI_71_2025. eCollection 2025.

DOI:10.25259/SNI_71_2025
PMID:40469361
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12134858/
Abstract

BACKGROUND

Chronic subdural hematoma (CSDH) recurrence remains a challenge, with risk factors still debated.

METHODS

A retrospective review of 185 CSDH cases surgically treated at Hospital Juárez de México (2014-2019) was conducted. Recurrence was defined as clinical deterioration with radiological re-expansion. Demographic, clinical, imaging and perioperative variables were analyzed statistically ( < 0.05).

RESULTS

The cohort included 145 males (78.4%) median age of 55 years. Head trauma was present in 75.7%. Hematomas were mostly chronic (69.2%), with 49.18% showing heterogeneous density. The surgical approaches used were single burr-hole (4.3%), double burr-hole (10.8%), and craniotomy (84.9%). Recurrence occurred in 16 cases (8.4%), primarily within a week. The significant risk factors for recurrence included thrombocytopenia (<130,000/uL, = 0.001) and prolonged partial thromboplastin time (>38.6 s, = 0.005). Craniotomy had lower recurrence (7%) than burr-holes ( = 0.053).

CONCLUSION

Thrombocytopenia and coagulopathy increase recurrence risk in CSDH. Craniotomy may reduce recurrence compared to burr-hole techniques. Further studies are needed to optimize surgical management.

摘要

背景

慢性硬膜下血肿(CSDH)复发仍是一个挑战,其危险因素仍存在争议。

方法

对墨西哥华雷斯医院(2014 - 2019年)手术治疗的185例CSDH病例进行回顾性研究。复发定义为临床病情恶化且影像学显示血肿再次扩大。对人口统计学、临床、影像学和围手术期变量进行统计学分析(<0.05)。

结果

该队列包括145名男性(78.4%),中位年龄55岁。75.7%的患者有头部外伤史。血肿大多为慢性(69.2%),49.18%表现为密度不均。采用的手术方法包括单钻孔(4.3%)、双钻孔(10.8%)和开颅手术(84.9%)。16例(8.4%)出现复发,主要在一周内。复发的显著危险因素包括血小板减少症(<130,000/μL, = 0.001)和活化部分凝血活酶时间延长(>38.6秒, = 0.005)。开颅手术的复发率(7%)低于钻孔手术( = 0.053)。

结论

血小板减少症和凝血功能障碍会增加CSDH的复发风险。与钻孔技术相比,开颅手术可能会降低复发率。需要进一步研究以优化手术管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f36c/12134858/99d0483a68e5/SNI-16-181-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f36c/12134858/87716d04987d/SNI-16-181-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f36c/12134858/e1ad71aad448/SNI-16-181-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f36c/12134858/8857aa8742b1/SNI-16-181-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f36c/12134858/0e76254043ee/SNI-16-181-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f36c/12134858/99d0483a68e5/SNI-16-181-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f36c/12134858/87716d04987d/SNI-16-181-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f36c/12134858/e1ad71aad448/SNI-16-181-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f36c/12134858/8857aa8742b1/SNI-16-181-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f36c/12134858/0e76254043ee/SNI-16-181-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f36c/12134858/99d0483a68e5/SNI-16-181-g005.jpg

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本文引用的文献

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Updates in Chronic Subdural Hematoma: Epidemiology, Etiology, Pathogenesis, Treatment, and Outcome.慢性硬脑膜下血肿的最新研究进展:流行病学、病因学、发病机制、治疗和预后。
World Neurosurg. 2020 Sep;141:339-345. doi: 10.1016/j.wneu.2020.06.140. Epub 2020 Jun 25.
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The Role of Medical Treatment in Chronic Subdural Hematoma.医学治疗在慢性硬膜下血肿中的作用
Asian J Neurosurg. 2018 Oct-Dec;13(4):976-983. doi: 10.4103/ajns.AJNS_13_17.
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Evidence based diagnosis and management of chronic subdural hematoma: A review of the literature.慢性硬膜下血肿的循证诊断与管理:文献综述
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Risk Factor Analysis for the Recurrence of Chronic Subdural Hematoma: A Review of 368 Consecutive Surgical Cases.慢性硬膜下血肿复发的危险因素分析:368例连续手术病例回顾
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History of Chronic Subdural Hematoma.慢性硬膜下血肿病史。
Korean J Neurotrauma. 2015 Oct;11(2):27-34. doi: 10.13004/kjnt.2015.11.2.27. Epub 2015 Oct 31.
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Independent predictors for recurrence of chronic subdural hematoma.慢性硬膜下血肿复发的独立预测因素。
J Korean Neurosurg Soc. 2015 Apr;57(4):266-70. doi: 10.3340/jkns.2015.57.4.266. Epub 2015 Apr 24.
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Actual and projected incidence rates for chronic subdural hematomas in United States Veterans Administration and civilian populations.美国退伍军人管理局和普通人群中慢性硬膜下血肿的实际发病率和预测发病率。
J Neurosurg. 2015 Nov;123(5):1209-15. doi: 10.3171/2014.9.JNS141550. Epub 2015 Mar 20.
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Nonsurgical treatment of chronic subdural hematoma with tranexamic acid.氨甲环酸治疗慢性硬脑膜下血肿的非手术治疗。
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Clin Neurol Neurosurg. 2013 Jul;115(7):981-4. doi: 10.1016/j.clineuro.2012.10.008. Epub 2012 Nov 3.
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