Oishi Takahiro, Nakamura Fumiko, Okuno Nao, Tamagaki Keisuke, Nakamura Yoshihiro, Sakuramoto Kazuhito, Kuwagata Yasuyuki
Department of Emergency and Critical Care Medicine Kansai Medical University Osaka Japan.
Acute Med Surg. 2025 Jun 3;12(1):e70069. doi: 10.1002/ams2.70069. eCollection 2025 Jan-Dec.
Laparotomy for gastrointestinal perforation is associated with a high risk of surgical site infection (SSI). The present study aimed to evaluate the effect of closed negative pressure wound therapy (NPWT) against SSI in patients undergoing laparotomy for gastrointestinal perforation.
This single-center, retrospective, observational study was carried out in a tertiary emergency medical center. We performed closed NPWT following emergency laparotomy for gastrointestinal perforation between May 2019 and May 2024, and compared it to standard dressings used between January 2016 and April 2019. Cases of open abdominal management were excluded. The primary outcome was the incidence of superficial and deep SSI between the two groups.
The closed NPWT group comprised 65 patients, and the standard dressing group comprised 62 patients. There were no significant differences in patient characteristics, comorbidities, operative indications, and wound classification between the two groups. The rate of superficial and deep SSI was significantly lower with closed NPWT (26.2% with closed NPWT vs. 45.2% with standard dressing, = 0.028).
The application of closed NPWT in patients undergoing laparotomy for gastrointestinal perforation was associated with a lower incidence of SSI compared with that of a standard surgical dressing.
剖腹手术治疗胃肠道穿孔与手术部位感染（SSI）的高风险相关。本研究旨在评估封闭式负压伤口治疗（NPWT）对接受剖腹手术治疗胃肠道穿孔患者的SSI的影响。
本单中心、回顾性、观察性研究在一家三级急诊医疗中心进行。我们在2019年5月至2024年5月期间对胃肠道穿孔患者进行急诊剖腹手术后采用封闭式NPWT，并将其与2016年1月至2019年4月期间使用的标准敷料进行比较。排除开放性腹部处理的病例。主要结局是两组之间浅表和深部SSI的发生率。
封闭式NPWT组有65例患者，标准敷料组有62例患者。两组在患者特征、合并症、手术指征和伤口分类方面无显著差异。封闭式NPWT的浅表和深部SSI发生率显著较低（封闭式NPWT为26.2%，标准敷料为45.2%，P = 0.028）。
与标准手术敷料相比，在接受剖腹手术治疗胃肠道穿孔的患者中应用封闭式NPWT与较低的SSI发生率相关。
