Zheng Cathy, Mowery Robert, Ali Sareena, Allen Camilla, Hoff Ryan T
Department of Medicine, University of Miami Miller School of Medicine, Miami, FL.
Elson S. Floyd College of Medicine, Washington State University, Spokane, WA.
ACG Case Rep J. 2025 Jun 4;12(6):e01720. doi: 10.14309/crj.0000000000001720. eCollection 2025 Jun.
Granular cell tumors (GCTs) are typically benign lesions that can occur in the gastrointestinal tract. Eosinophilic gastrointestinal disease, including eosinophilic esophagitis (EoE), is an immune-mediated condition characterized by eosinophil-predominant inflammation in the gastrointestinal tract. We review previously reported cases of EoE associated with GCTs. To our knowledge, we present the first case of esophageal GCT in a patient with a long history of eosinophilic gastrointestinal disease and likely several years of active EoE before esophageal GCT diagnosis.
颗粒细胞瘤（GCTs）是一种通常发生在胃肠道的良性病变。嗜酸性胃肠道疾病，包括嗜酸性食管炎（EoE），是一种免疫介导的疾病，其特征是胃肠道中以嗜酸性粒细胞为主的炎症。我们回顾了先前报道的与GCTs相关的EoE病例。据我们所知，我们报告了首例患有长期嗜酸性胃肠道疾病且在食管GCT诊断前可能有多年活动性EoE的患者的食管GCT病例。
