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与嗜酸性胃肠道疾病相关的食管颗粒细胞瘤

Esophageal Granular Cell Tumor Associated With Eosinophilic Gastrointestinal Disease.

作者信息

Zheng Cathy, Mowery Robert, Ali Sareena, Allen Camilla, Hoff Ryan T

机构信息

Department of Medicine, University of Miami Miller School of Medicine, Miami, FL.

Elson S. Floyd College of Medicine, Washington State University, Spokane, WA.

出版信息

ACG Case Rep J. 2025 Jun 4;12(6):e01720. doi: 10.14309/crj.0000000000001720. eCollection 2025 Jun.

Abstract

Granular cell tumors (GCTs) are typically benign lesions that can occur in the gastrointestinal tract. Eosinophilic gastrointestinal disease, including eosinophilic esophagitis (EoE), is an immune-mediated condition characterized by eosinophil-predominant inflammation in the gastrointestinal tract. We review previously reported cases of EoE associated with GCTs. To our knowledge, we present the first case of esophageal GCT in a patient with a long history of eosinophilic gastrointestinal disease and likely several years of active EoE before esophageal GCT diagnosis.

摘要

颗粒细胞瘤(GCTs)是一种通常发生在胃肠道的良性病变。嗜酸性胃肠道疾病,包括嗜酸性食管炎(EoE),是一种免疫介导的疾病,其特征是胃肠道中以嗜酸性粒细胞为主的炎症。我们回顾了先前报道的与GCTs相关的EoE病例。据我们所知,我们报告了首例患有长期嗜酸性胃肠道疾病且在食管GCT诊断前可能有多年活动性EoE的患者的食管GCT病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b16/12136658/fc056c670065/ac9-12-e01720-g001.jpg

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