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[照射质量对无法手术的支气管癌患者生存率的影响(作者译)]

[The influence of quality of irradiation on survival in inoperable bronchial carcinoma (author's transl)].

作者信息

Rey G, Haase W

出版信息

Rontgenblatter. 1977 Apr;30(4):202-10.

PMID:404698
Abstract

Irradiation of inoperable bronchial carcinoma with constant ortho-volt technique has worse results than with mobile irradiation, since the individual dosage in several fields can be raised without damaging the skin. With mega-voltage limits of skin tolerance, changed absorption or protection of healthy tissues are absent, so that it is easier to deliver doses affective on the tumor. Survival-rates can be related to dosage. During the first few years similar doses of mega-voltage lead to more frequent survival. In part such results depend on differences in standard dosage with the various techniques. More important for the worse results of orthovoltage treatment are the higher doses, the greater volume of irradiation and scatter which may cause greater damage to immunity. 5 years survival of patients with a central inoperable bronchial carcinoma is hardly altered but during the first 2-3 years megavolt therapy is clearly more effective.

摘要

用恒定正交电压技术照射无法手术的支气管癌,其效果比移动照射更差,因为在几个照射野中可以提高个体剂量而不损伤皮肤。在兆伏电压下,不存在皮肤耐受性限制、健康组织吸收或保护的改变,因此更容易给予对肿瘤有效的剂量。生存率与剂量有关。在最初几年,相似剂量的兆伏电压照射导致更频繁的生存。部分此类结果取决于不同技术在标准剂量上的差异。正交电压治疗效果较差的更重要原因是较高的剂量、更大的照射体积和散射,这可能对免疫力造成更大损害。中心型无法手术的支气管癌患者的5年生存率几乎没有改变,但在最初2 - 3年,兆伏治疗明显更有效。

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