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针刺联合康复训练治疗脑卒中临床疗效及潜在机制的多维度评价:一项基于多评价指标的研究

Multidimensional evaluation of the clinical efficacy and potential mechanisms of acupuncture combined with rehabilitation training in the treatment of stroke: a study based on multiple evaluation indicators.

作者信息

Xie Jingjun, Li Jinxia, Sun Qi, Jiang Jie

机构信息

The First People's Hospital of Huzhou, Huzhou, Zhejiang, China.

Huzhou Hospital of Traditional Chinese Medicine, Affiliated to Zhejiang Chinese Medical University, Huzhou, Zhejiang, China.

出版信息

Front Neurol. 2025 May 21;16:1573073. doi: 10.3389/fneur.2025.1573073. eCollection 2025.

DOI:10.3389/fneur.2025.1573073
PMID:40470494
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12133552/
Abstract

OBJECTIVE

This study aims to explore the therapeutic effects and potential mechanisms of acupuncture combined with rehabilitation training on stroke patients.

METHODS

A total of 120 stroke patients were randomly divided into a control group (Group A), a rehabilitation training group (Group B), and an acupuncture combined with rehabilitation training group (Group C), with 40 patients in each group. The National Institute of Health Stroke Scale (NIHSS) for neurological deficit, the Barthel Index for activities of daily living ability were evaluated before treatment, 4, 8, and 12 weeks after treatment. Additionally, the levels of serum brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), and inflammatory factors (IL-6, TNF-α) were detected.

RESULTS

The acupuncture combined with rehabilitation training group (Group C) was significantly superior to the other two groups (Group A and Group B) in improving neurological function, activities of daily living ability, and regulating serum factor levels.

CONCLUSION

Acupuncture combined with rehabilitation training is an effective treatment regimen for stroke, providing a theoretical and practical basis for clinical application.

摘要

目的

本研究旨在探讨针刺结合康复训练对脑卒中患者的治疗效果及潜在机制。

方法

将120例脑卒中患者随机分为对照组(A组)、康复训练组(B组)和针刺结合康复训练组(C组),每组40例。在治疗前、治疗后4周、8周和12周评估神经功能缺损的美国国立卫生研究院卒中量表(NIHSS)、日常生活活动能力的巴氏指数。此外,检测血清脑源性神经营养因子(BDNF)、神经生长因子(NGF)和炎症因子(IL-6、TNF-α)水平。

结果

针刺结合康复训练组(C组)在改善神经功能、日常生活活动能力及调节血清因子水平方面明显优于其他两组(A组和B组)。

结论

针刺结合康复训练是治疗脑卒中的有效方案,为临床应用提供了理论和实践依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/700c/12133552/bf05ced623c3/fneur-16-1573073-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/700c/12133552/bf05ced623c3/fneur-16-1573073-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/700c/12133552/bf05ced623c3/fneur-16-1573073-g0001.jpg

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