Hohl Corinne M, Okpani Arnold Ikedichi, Kuziemsky Craig
University of British Columbia, Vancouver, British Columbia, Canada.
Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada.
Healthc Manage Forum. 2025 Jun 5;38(5):8404704251346951. doi: 10.1177/08404704251346951.
Adverse Drug Events (ADEs) are unintended and harmful events related to medication use. Many ADEs recur because patients are unintentionally re-exposed to medications that previously caused harm. To help address this, we designed ActionADE, an interoperable Health Information Technology (HIT) that allows clinicians to communicate ADEs across health sectors. We completed ethnographic workplace observations and a systematic review to inform design. After piloting, we integrated ActionADE with the provincial medication dispensing database to alert pharmacists when patients seek to fill a prescription for the same or a same-class drug as one that previously caused harm. Co-design, application of clinically meaningful field labels and data standards, and integration with other health information systems were critical to ActionADE's functionality and use. However, health system decision-makers need to proactively plan for how to spread and scale pilot project in the HIT ecosystem to ensure public benefit from successful innovation.
药品不良事件（ADEs）是与药物使用相关的意外且有害的事件。许多药品不良事件会再次发生，因为患者会无意中再次接触到先前造成伤害的药物。为了帮助解决这一问题，我们设计了ActionADE，这是一种可互操作的健康信息技术（HIT），它允许临床医生在不同健康部门之间交流药品不良事件。我们完成了人种学工作场所观察和系统综述，以为设计提供参考。在进行试点之后，我们将ActionADE与省级药物配药数据库集成，以便在患者寻求开具与先前造成伤害的药物相同或同类药物的处方时提醒药剂师。共同设计、应用具有临床意义的字段标签和数据标准以及与其他健康信息系统集成对于ActionADE的功能和使用至关重要。然而，卫生系统决策者需要积极规划如何在健康信息技术生态系统中推广和扩大试点项目，以确保公众从成功的创新中受益。
