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钚-239诱发雄性小鼠的可遗传易位

239Plutonium-induced heritable translocations in male mice.

作者信息

Generoso W M, Cain K T, Cacheiro N L, Cornett C V

出版信息

Mutat Res. 1985 Oct;152(1):49-52. doi: 10.1016/0027-5107(85)90045-4.

DOI:10.1016/0027-5107(85)90045-4
PMID:4047084
Abstract

This study was conducted to estimate the frequency of transmitted reciprocal translocations per rad of exposure to alpha particles from [239Pu]citrate. Data indicate that the rate of induction of heritable translocations is related linearly to the duration of spermatogonia stem cell exposure. The estimated increase in heritable translocations per rad of exposure of the stem cell to alpha particles is in the range of 1.45-2.91 X 10(-5)/gamete.

摘要

本研究旨在估算每拉德暴露于柠檬酸[239Pu]产生的α粒子所致相互易位的传递频率。数据表明，可遗传易位的诱导率与精原干细胞暴露持续时间呈线性相关。干细胞每拉德暴露于α粒子后，可遗传易位的估计增加范围为1.45 - 2.91×10^(-5)/配子。

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1
239Plutonium-induced heritable translocations in male mice.钚-239诱发雄性小鼠的可遗传易位
Mutat Res. 1985 Oct;152(1):49-52. doi: 10.1016/0027-5107(85)90045-4.
2
Cytogenetic effects of protracted exposures to alpha-particles from plutonium-239 and to gamma-rays from cobalt-60 compared in male mice.比较雄性小鼠长期暴露于钚 - 239的α粒子和钴 - 60的γ射线后的细胞遗传学效应。
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[Cytogenetic effect of 238Pu alpha radiation on the germ cells of male mice].[238Puα辐射对雄性小鼠生殖细胞的细胞遗传学效应]
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[The mutagenic effect of different types of irradiation on the sex cells of male mice. VIII. Frequency of development of reciprocal translocations in the spermatogonia of mice subjected to chronic gamma-irradiation].[不同类型辐射对雄性小鼠生殖细胞的诱变作用。VIII. 慢性γ辐射小鼠精原细胞中相互易位的发生频率]
Genetika. 1975;11(3):81-6.