钚-239诱发雄性小鼠的可遗传易位
239Plutonium-induced heritable translocations in male mice.
作者信息
Generoso W M, Cain K T, Cacheiro N L, Cornett C V
出版信息
Mutat Res. 1985 Oct;152(1):49-52. doi: 10.1016/0027-5107(85)90045-4.
PMID:4047084
Abstract
This study was conducted to estimate the frequency of transmitted reciprocal translocations per rad of exposure to alpha particles from [239Pu]citrate. Data indicate that the rate of induction of heritable translocations is related linearly to the duration of spermatogonia stem cell exposure. The estimated increase in heritable translocations per rad of exposure of the stem cell to alpha particles is in the range of 1.45-2.91 X 10(-5)/gamete.
摘要
本研究旨在估算每拉德暴露于柠檬酸[239Pu]产生的α粒子所致相互易位的传递频率。数据表明，可遗传易位的诱导率与精原干细胞暴露持续时间呈线性相关。干细胞每拉德暴露于α粒子后，可遗传易位的估计增加范围为1.45 - 2.91×10^(-5)/配子。
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