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改良热调制用于脊柱骨样骨瘤安全射频消融的初步研究

Modified thermal modulation for safe radiofrequency ablation of spinal osteoid osteoma: a pilot study.

作者信息

Singh Dharmendra Kumar, Kumar Nishith, Bhardwaj Krishna, Jalan Divesh, Rustagi Ashish, Saifi Alfa Shamim, Singh Upinderjeet

机构信息

Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

出版信息

Eur Spine J. 2025 Aug;34(8):3540-3548. doi: 10.1007/s00586-025-08956-0. Epub 2025 Jun 5.

Abstract

PURPOSE

In our pilot study, we modified the temperature and duration of radiofrequency ablation of spinal osteoid osteoma to minimize the risk of neural damage without compromising adequate ablation.

METHODS

Seven patients were enrolled in this study after obtaining written informed consent. RFA was done in prone position under CT-guidance (256-slice Siemens Somatom scanner) under general anesthesia. Additional neuroprotection was provided in form of pneumo-dissection and hydro-dissection into epidural space via entry from a contralateral inter-laminar space. Ablation was done using RITA XL-Starburst ™ multi-tined probe as a component of Angiodynamics monopolar RF ablation system. Stepwise graded increase in temperature was performed in three phases (Induction, Amplification and Residual burn). Post operative evaluation was done using VAS and four hourly sensory and motor examinations. Clinical success was defined as post-operative day 1 VAS of ≤ 3. Follow up was done at 1 month,3 months and 6 months and neurological status was evaluated at all follow ups.

RESULT

We evaluated a novel technique of ablation using graded thermal modulation in seven patients of spinal osteoid osteoma without any adverse injuries or sensory-motor neurological deficits. All seven patients fulfilled the criteria of technical and clinical success and demonstrated a significant reduction in VAS on the first post-operative day with no residual symptoms on serial follow ups.

CONCLUSION

Modified RFA using graded thermal modulation has shown promising result for safe ablation of spinal osteoid osteoma in our pilot study.

摘要

目的

在我们的初步研究中,我们对脊柱骨样骨瘤的射频消融温度和持续时间进行了调整,以在不影响充分消融的情况下将神经损伤风险降至最低。

方法

在获得书面知情同意后,7名患者纳入本研究。在全身麻醉下,于CT引导下(256层西门子Somatom扫描仪)采用俯卧位进行射频消融。通过对侧椎板间隙进入硬膜外间隙,以气体分离和水分离的形式提供额外的神经保护。使用RITA XL-Starburst™ 多针探头作为Angiodynamics单极射频消融系统的组件进行消融。分三个阶段(诱导、增强和残留烧灼)逐步分级升高温度。术后使用视觉模拟评分法(VAS)以及每四小时进行一次感觉和运动检查进行评估。临床成功定义为术后第1天VAS≤3。在1个月、3个月和6个月进行随访,并在所有随访中评估神经状态。

结果

我们评估了一种在7例脊柱骨样骨瘤患者中使用分级热调制的新型消融技术,未出现任何不良损伤或感觉运动神经功能缺损。所有7例患者均符合技术和临床成功标准,术后第1天VAS显著降低,系列随访中无残留症状。

结论

在我们的初步研究中,使用分级热调制的改良射频消融术在安全消融脊柱骨样骨瘤方面显示出了有前景的结果。

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