Gadalla Ramy, Nair Mani Nathan, Spevak Christopher, Wang Georgia, Mukherjee Debraj, Corredor Alonso Guillermo Ernesto, Syed Hasan, Dowlati Ehsan, Ramsey Benjamin, Habib Mark, Yanni Baher
Georgetown University School of Medicine, Washington, DC, USA.
Department of Neurosurgery, Georgetown University School of Medicine, Washington, DC, USA.
Pain Physician. 2025 Jul;28(4):E445-E456.
Facet joint syndrome accounts for many patients' chronic neck and low back pain. Current interventional treatment options for these conditions include radiofrequency ablation (RFA) and endoscopic rhizotomy (ER), which target the medial branch of the dorsal ramus innervating the facet joint capsule. RFA is a percutaneous procedure in which radiofrequency waves ablate the medial branch. ER, a newer and more invasive procedure, is typically reserved for patients who have not responded to RFA. This retrospective cohort study aims to compare the postoperative pain level (VAS score), duration of pain relief, and opioid intake among patients who have received ER to those of patients who have received RFA. The results of these operations at all 3 spinal levels will be examined.
To evaluate the longevity and quality of pain relief status post RFA versus ER for facet joint syndrome.
A retrospective cohort study that includes patients treated with sequentially with RFA and then ER. The study analyzed the endpoint after each procedure for each spinal region.
Three urban neuro-spine centers.
The study utilized the Strengthening the Reporting of Observational Studies in Epidemiology Analysis (STROBE) initiative. Patients with positive diagnostic medial branch blocks (80% pain relief) obtained RFA and ER, in sequence. The region of procedure (cervical, thoracic, or lumbar), morphine milligram equivalent (MME) requirements, VAS pain scores before and after the procedure, and duration of relief were collected from the electronic medical records. Patient follow-ups were conducted at 3 months, 6 months, 9 months, 12 months, and after 12 months.
Among the 234 patients who underwent 511 RFAs and 386 ERs, ER was associated with significantly better efficacy than RFA in VAS scores (P = 0.001), opioid consumption (P = 0.0442), and duration of pain relief (P < 0.0001), with all spinal levels analyzed aggregately. However, with each spinal region analyzed separately, ER was associated with significantly lower VAS scores only in the lumbar spine (P < 0.0001) while the longer duration of relief persisted across all regions (P < 0.05).
The study design was retrospective and nonrandomized. The study also did not utilize functional scales, e.g., the Oswestry Disability Index. Finally, ER is not available to the public.
Both procedures decrease pain levels and opioid consumption significantly. ER is associated with lower pain levels, lower opioid consumption, and a longer duration of pain relief than RFA in the aggregate data. However, when each spinal region is re-analyzed separately, ER results in significantly lower pain levels only in the lumbar spine. Nonetheless, ER continues to provide a longer relief duration than does RFA in all spinal regions. Deploying ER sooner in patients with facet joint pain may be more beneficial than performing RFA and waiting for pain symptoms to recur.
小关节综合征是许多患者慢性颈痛和腰痛的病因。目前针对这些病症的介入治疗方法包括射频消融术(RFA)和内镜下神经根切断术(ER),这些方法针对支配小关节囊的背侧支内侧支。RFA是一种经皮手术,利用射频波消融内侧支。ER是一种更新且更具侵入性的手术,通常用于对RFA无反应的患者。这项回顾性队列研究旨在比较接受ER治疗的患者与接受RFA治疗的患者术后疼痛程度(视觉模拟评分法[VAS]评分)、疼痛缓解持续时间和阿片类药物摄入量。将检查所有三个脊柱节段这些手术的结果。
评估RFA与ER治疗小关节综合征后疼痛缓解状态的持续时间和质量。
一项回顾性队列研究,纳入先后接受RFA和ER治疗的患者。该研究分析了每个脊柱区域每次手术后的终点指标。
三个城市神经脊柱中心。
本研究采用了加强流行病学观察性研究报告(STROBE)倡议。诊断性内侧支阻滞阳性(疼痛缓解80%)的患者依次接受RFA和ER。从电子病历中收集手术区域(颈椎、胸椎或腰椎)、吗啡毫克当量(MME)需求量、手术前后的VAS疼痛评分以及缓解持续时间。在3个月、6个月、9个月、12个月以及12个月后对患者进行随访。
在接受511次RFA和386次ER的234例患者中,综合分析所有脊柱节段,ER在VAS评分(P = 0.001)、阿片类药物消耗量(P = 0.0442)和疼痛缓解持续时间(P < 0.0001)方面的疗效明显优于RFA。然而,分别分析每个脊柱区域时,ER仅在腰椎区域与显著更低的VAS评分相关(P < 0.0001),而在所有区域疼痛缓解持续时间更长这一情况仍然存在(P < 0.05)。
本研究设计为回顾性且非随机。该研究也未使用功能量表,例如奥斯威斯功能障碍指数。最后,ER并非公众都可使用。
两种手术均能显著降低疼痛程度和阿片类药物消耗量。综合数据显示,与RFA相比,ER与更低的疼痛程度、更低的阿片类药物消耗量以及更长的疼痛缓解持续时间相关。然而,当分别重新分析每个脊柱区域时,ER仅在腰椎区域导致疼痛程度显著更低。尽管如此,在所有脊柱区域ER提供的缓解持续时间仍比RFA更长。对于小关节疼痛患者,尽早采用ER可能比先进行RFA并等待疼痛症状复发更为有益。