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基于视频会议的认知行为疗法对接受药物治疗的成人注意力缺陷多动障碍患者的疗效:一项随机、评估者盲法、对照试验

Videoconference-Based Cognitive Behavioral Therapy in Medication-Treated Adults with Attention-Deficit/Hyperactivity Disorder: A Randomized, Assessor-Blinded, Controlled Trial.

作者信息

Eto Aiko, Endo Ayumu, Yoshida Tokiko, Seki Yoichi, Taguchi Kayoko, Hongo Minako, Takahashi Kohei, Shiko Yuki, Hirano Yoshiyuki, Shimizu Eiji

机构信息

Department of Cognitive Behavioral Physiology, Graduate School of Medicine, Chiba University, Chiba, Japan.

Research Center for Child Mental Development, Chiba University, Chiba, Japan.

出版信息

Psychother Psychosom. 2025;94(5):343-357. doi: 10.1159/000546539. Epub 2025 Jun 5.

Abstract

INTRODUCTION

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder that frequently persists into adulthood. Pharmacotherapies are effective but have side effects and dropout risks. Videoconference-based cognitive behavioral therapy (vCBT) has emerged as a promising intervention, particularly for improving treatment accessibility. This study aimed to evaluate the efficacy of vCBT in adults with ADHD compared to treatment-as-usual (TAU) using a randomized, assessor-blinded, controlled trial design.

METHODS

Thirty participants (aged 18-65 years) with ADHD were randomly assigned to either the 12-session individual vCBT intervention as an adjunct to TAU or TAU group. The primary outcome was the change in the total score on the ADHD Rating Scale-IV (ADHD-RS-IV) with adult prompts by a blinded assessor at 12 weeks from baseline. Secondary outcomes included self-reported measures of ADHD symptoms using the Conners' Adult ADHD Rating-Self-Report, quality of life (QOL) using the Euro QOL 5 Dimension-5 Level, functional impairment using the Sheehan Disability Scale, depression, anxiety, and self-esteem.

RESULTS

All of the participants received pharmacotherapy. Participants in the vCBT group (n = 15) demonstrated a significantly greater reduction in ADHD-RS-IV total score than those in the TAU group (vCBT -9.02 vs. TAU 0.84, p = 0.0007, effect size -1.46). Significant improvements in self-reported inattention, hyperactivity, impulsivity, QOL, and work/school performance were observed in favor of vCBT.

CONCLUSION

This study highlights the efficacy of vCBT as a viable and accessible intervention for adults with ADHD, particularly in reducing core symptoms and enhancing QOL and functional outcomes. vCBT is an important alternative treatment, especially for patients who remain symptomatic after pharmacotherapy.

摘要

引言

注意力缺陷多动障碍(ADHD)是一种神经发育障碍,常常持续至成年期。药物治疗虽有效,但存在副作用和停药风险。基于视频会议的认知行为疗法(vCBT)已成为一种有前景的干预措施,尤其是在提高治疗可及性方面。本研究旨在采用随机、评估者盲法、对照试验设计,评估vCBT与常规治疗(TAU)相比对成人ADHD患者的疗效。

方法

30名患有ADHD的参与者(年龄在18 - 65岁之间)被随机分配至接受12节个体vCBT干预作为TAU辅助治疗的组或TAU组。主要结局是由盲法评估者在基线后12周根据成人提示的ADHD评定量表-IV(ADHD-RS-IV)总分的变化。次要结局包括使用康纳斯成人ADHD自评量表进行的ADHD症状自评、使用欧洲五维健康量表5水平进行的生活质量(QOL)评估、使用希恩残疾量表进行的功能损害评估、抑郁、焦虑和自尊。

结果

所有参与者均接受了药物治疗。vCBT组(n = 15)的参与者在ADHD-RS-IV总分上的降低幅度显著大于TAU组(vCBT组降低9.02分,TAU组降低0.84分,p = 0.0007,效应量为-1.46)。观察到在自我报告的注意力不集中、多动、冲动、生活质量和工作/学习表现方面,vCBT组有显著改善。

结论

本研究强调了vCBT作为一种对成人ADHD患者可行且可及的干预措施的疗效,尤其是在减轻核心症状以及提高生活质量和功能结局方面。vCBT是一种重要的替代治疗方法,特别是对于药物治疗后仍有症状的患者。

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