Lapierre Alexandra, Nkeshimana Audace, Yanchar Natalie, Haas Barbara, Evans David C, Ziesman Markus, McFarlan Amanda W, Mercier Éric, Lampron Jacynthe, Tillmann Bourke, Moore Lynne
Department of Social and Preventive Medicine, Université Laval, Quebec City, QC, Canada.
Research Centre, Centre Hospitalier Universitaire (CHU) de Québec, Université Laval, Quebec City, QC, Canada.
Can J Anaesth. 2025 Jul;72(7):1130-1139. doi: 10.1007/s12630-025-02964-w. Epub 2025 Jun 5.
Trauma systems encompass injury prevention, prehospital care, acute care, rehabilitation, and community integration. The proportion of out-of-hospital injury deaths may indicate the effectiveness of trauma systems, particularly in prevention and prehospital care. In the absence of Canadian data, we aimed to estimate this proportion nationally and by province and analyze variations by age, sex, and year.
We conducted a historical cohort study to analyze aggregate data on hospital discharges and mortality statistics covering injury-related deaths in Canadian provinces and territories from 2017 to 2020. We included deaths from all Canadian provinces and territories except Quebec, for which data on in-hospital deaths were unavailable. We calculated the proportions of out-of-hospital deaths with 95% confidence intervals. We used robust Poisson models to assess provincial variation, adjusting for age, sex, and year for Ontario, Alberta, and British Columbia (the volumes were too low in the other provinces). We conducted subgroup analyses for age group, sex, year, and injury mechanism.
Canada recorded 64,725 injury-related deaths between 2017 and 2020 (32.3% ≥ age 65 yr; 34.5% female), with 48% occurring outside of hospitals globally and 80% in < 65-yr-olds. Proportions of out-of-hospital deaths ranged from 30% in the Atlantic provinces to 58% in Saskatchewan. After adjusting for age, sex, and year, Alberta had a 13% higher risk of out-of-hospital mortality than Ontario (reference standard), while British Columbia had a 26% lower risk. Subgroup analyses revealed variations across age groups, sex, and years.
Half of all injury deaths in Canada between 2017 and 2020 occured outside of hospitals. This proportion varied by province, possibly suggesting differences in the development and maturity of provincial trauma systems. Future studies should strive to identify modifiable determinants of these interprovincial variations to inform public health strategies.
创伤系统涵盖伤害预防、院前护理、急性护理、康复以及社区融合。院外伤害死亡比例可表明创伤系统的有效性,尤其是在预防和院前护理方面。由于缺乏加拿大的数据,我们旨在估算全国及各省的这一比例,并分析年龄、性别和年份的差异。
我们进行了一项历史性队列研究,以分析2017年至2020年加拿大各省和地区与伤害相关死亡的医院出院汇总数据和死亡率统计数据。我们纳入了除魁北克省以外所有加拿大省份和地区的死亡数据,魁北克省没有住院死亡数据。我们计算了院外死亡比例及95%置信区间。我们使用稳健泊松模型评估各省差异,并对安大略省、艾伯塔省和不列颠哥伦比亚省的年龄、性别和年份进行了调整(其他省份的数据量太少)。我们对年龄组、性别、年份和伤害机制进行了亚组分析。
2017年至2020年期间,加拿大记录了64,725例与伤害相关的死亡(65岁及以上者占32.3%;女性占34.5%),全球48%的死亡发生在院外,65岁以下者占80%。院外死亡比例从大西洋省份的30%到萨斯喀彻温省的58%不等。在对年龄、性别和年份进行调整后,艾伯塔省院外死亡率比安大略省(参考标准)高13%,而不列颠哥伦比亚省则低26%。亚组分析揭示了不同年龄组之间、性别之间和年份之间的差异。
2017年至2020年期间,加拿大所有伤害死亡中有一半发生在院外。这一比例因省份而异,可能表明各省创伤系统的发展和成熟程度存在差异。未来的研究应努力确定这些省际差异的可改变决定因素,为公共卫生策略提供信息。