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兽医药理学统计方法完整报告的建议。

Recommendations for a Complete Reporting of Statistical Methods in Veterinary Pharmacology.

作者信息

Villarino Nicolas F

机构信息

Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA, USA.

出版信息

J Vet Pharmacol Ther. 2025 Jul;48(4):221-233. doi: 10.1111/jvp.70001. Epub 2025 Jun 6.

DOI:10.1111/jvp.70001
PMID:40474839
Abstract

Reproducibility and replicability of study results are crucial for advancing scientific knowledge. However, achieving these goals is often challenging, which can compromise the credibility of research and incur immeasurable costs for the progression of science. Despite efforts to standardize reporting with guidelines, the description of statistical methodology in manuscripts often remains insufficient, limiting the possibility of replicating scientific studies. A thorough, transparent, and complete report of statistical methods is essential for understanding study results and mimicking statistical strategies implemented in previous studies. This review outlines the key statistical reporting elements required to replicate statistical methods in most current veterinary pharmacology studies. It also offers a protocol for statistical reporting to aid in manuscript preparation and to assist trialists and editors in the collective strive for advancing veterinary pharmacology research.

摘要

研究结果的可重复性和可再现性对于推动科学知识发展至关重要。然而,实现这些目标往往具有挑战性,这可能会损害研究的可信度,并给科学进步带来不可估量的成本。尽管努力通过指南使报告标准化,但手稿中统计方法的描述往往仍然不足,限制了重复科学研究的可能性。对统计方法进行全面、透明和完整的报告对于理解研究结果以及模仿先前研究中实施的统计策略至关重要。本综述概述了在当前大多数兽医药理学研究中重复统计方法所需的关键统计报告要素。它还提供了一个统计报告方案,以帮助撰写手稿,并协助试验者和编辑共同努力推动兽医药理学研究。

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本文引用的文献

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试验报告中结果报告指南:CONSORT-结果2022扩展版
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Pharmacokinetics of maropitant citrate in Rhode Island Red chickens (Gallus gallus domesticus) following subcutaneous administration.柠檬酸马罗匹坦在皮下给药后的 Rhode Island Red 鸡(Gallus gallus domesticus)中的药代动力学。
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