Suokas Kimmo, Niemi Ripsa, Gutvilig Mai, J McGrath John, Komulainen Kaisla, Suvisaari Jaana, Elovainio Marko, Lumme Sonja, Pirkola Sami, Hakulinen Christian
Department of Psychology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Faculty of Social Sciences, Tampere University, Tampere, Finland.
Epidemiol Psychiatr Sci. 2025 Jun 6;34:e31. doi: 10.1017/S2045796025100061.
Previous studies have estimated the lifetime incidence, age of onset and prevalence of mental disorders, but none have used nationwide data covering both primary and secondary care, even though mental disorders are commonly treated in primary care. We aimed to determine lifetime incidence, age-specific incidence, age of onset and service utilization for diagnosed mental disorders.
This register-based cohort study followed the entire population of Finland from 2000 to 2020. We estimated the cumulative incidence of diagnosed mental disorders with the Aalen-Johansen estimator, accounting for competing risks such as death and emigration. We also calculated age-specific incidence and 12-month service utilization as of 31 December 2019, providing diagnosis-, age- and gender-specific estimates.
We followed 6.4 million individuals for 98.5 million person-years. By age 100, lifetime incidence of any diagnosed mental disorder was 76.7% (95% CI, 76.6-76.7) in women and 69.7% (69.6-69.8) in men; in psychiatric secondary care, it was 39.7% (39.6-39.8) and 31.5% (31.4-31.6). At age 75, stricter estimates for non-organic disorders (ICD-10: F10-F99) were 65.6% (65.5-65.7) for women and 60.0% (59.9-60.1). Anxiety disorders (F40-F48) had the highest cumulative incidence. Median age of onset of non-organic mental disorders was 24.1 (interquartile range, 14.8-43.3 years) in women and 20.0 (interquartile range, 7.3-42.2 years) in men. Service utilization within 12 months was 9.0% for women and 7.7% for men.
Most, though not all, individuals experience at least one type of mental disorder, often during youth. Capturing the overall occurrence of mental disorders requires including both primary and secondary care data.
以往的研究已经估算了精神障碍的终生发病率、发病年龄和患病率,但尽管精神障碍通常在初级保健机构进行治疗,却没有一项研究使用涵盖初级和二级保健的全国性数据。我们旨在确定已诊断精神障碍的终生发病率、特定年龄发病率、发病年龄和服务利用情况。
这项基于登记册的队列研究对2000年至2020年芬兰的全体人口进行了跟踪。我们使用Aalen-Johansen估计量估算已诊断精神障碍的累积发病率,并考虑了死亡和移民等竞争风险。我们还计算了截至2019年12月31日的特定年龄发病率和12个月的服务利用情况,提供了按诊断、年龄和性别划分的估计值。
我们对640万人进行了9850万人年的跟踪。到100岁时,任何已诊断精神障碍的终生发病率在女性中为76.7%(95%CI,76.6 - 76.7),在男性中为69.7%(69.6 - 69.8);在精神科二级保健中,分别为39.7%(39.6 - 39.8)和31.5%(31.4 - 31.6)。在75岁时,对非器质性障碍(ICD - 10:F10 - F99)更严格的估计在女性中为65.6%(65.5 - 65.7),在男性中为60.0%(59.9 - 60.1)。焦虑障碍(F40 - F48)的累积发病率最高。非器质性精神障碍的发病年龄中位数在女性中为24.1岁(四分位间距,14.8 - 43.3岁),在男性中为20.0岁(四分位间距,7.3 - 42.2岁)。女性12个月内的服务利用率为9.0%,男性为7.7%。
大多数(尽管不是全部)个体至少经历过一种精神障碍,且通常在年轻时。要掌握精神障碍的总体发病情况,需要纳入初级和二级保健数据。