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在基于登记册的研究中加强对非情感性精神病的识别。

Enhancing identification of nonaffective psychosis in register-based studies.

作者信息

Holm Minna, Suokas Kimmo, Liukko Emmi, Lindgren Maija, Näätänen Petri, Kärkkäinen Jukka, Salokangas Raimo K R, Suvisaari Jaana

机构信息

Finnish Institute for Health and Welfare, Equality Unit, Helsinki, Finland.

Finnish Psychiatric Association, Helsinki, Finland.

出版信息

Schizophrenia (Heidelb). 2024 Feb 19;10(1):20. doi: 10.1038/s41537-024-00444-6.

DOI:10.1038/s41537-024-00444-6
PMID:38374191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10876989/
Abstract

The Finnish Quality of Psychosis Care Register assesses nonaffective psychosis (NAP) care, acknowledging treatment outside specialized psychiatric services. This approach, while providing a holistic view, raises concerns about diagnostic inaccuracies. Here, we studied situations where the register-based diagnosis might be inaccurate, and whether the first episode can be reliably identified using a 14-year wash-out period. People with first register-based NAP (ICD-10 F20-F29) between years 2010 and 2018 and without NAP diagnoses in 1996-2009 were identified from the Care Register for Health Care. A diagnosis of NAP was deemed unreliable before age 7, when dementia preceded NAP diagnosis, and when a NAP diagnosis had been assigned at admission or during psychiatric hospitalization but was not confirmed by discharge diagnosis. Despite a 14-year follow-back the first register diagnosis may miss the first treatment episode in older patients. Register-based studies on psychotic disorders should pay attention to exclusion criteria and to the definition of treatment onset.

摘要

芬兰精神病护理质量登记册评估非情感性精神病(NAP)护理情况,认可在专门精神病服务机构之外的治疗。这种方法虽能提供全面视角,但引发了对诊断不准确的担忧。在此,我们研究了基于登记册的诊断可能不准确的情况,以及是否可通过14年的洗脱期可靠地识别首次发作。从医疗保健护理登记册中识别出2010年至2018年间首次基于登记册诊断为NAP(国际疾病分类第十版F20 - F29)且在1996 - 2009年期间无NAP诊断的患者。在7岁之前、痴呆先于NAP诊断以及在入院时或精神科住院期间被诊断为NAP但出院诊断未确认时,NAP诊断被视为不可靠。尽管进行了14年的追溯,首次登记诊断可能会遗漏老年患者的首次治疗发作。基于登记册的精神病障碍研究应关注排除标准和治疗起始的定义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77fe/10876989/480c5d450b8a/41537_2024_444_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77fe/10876989/a92c12ec6c3f/41537_2024_444_Fig1_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77fe/10876989/407ee35a99f1/41537_2024_444_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77fe/10876989/480c5d450b8a/41537_2024_444_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77fe/10876989/a92c12ec6c3f/41537_2024_444_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77fe/10876989/8fdbdbc317ed/41537_2024_444_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77fe/10876989/650427d0cb6f/41537_2024_444_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77fe/10876989/407ee35a99f1/41537_2024_444_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77fe/10876989/480c5d450b8a/41537_2024_444_Fig5_HTML.jpg

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