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肝硬化血小板减少症管理的中国专家共识

Chinese Expert Consensus for the Management of Thrombocytopenia in Cirrhosis.

作者信息

Xu Xiaoyuan, Guan Yujuan, Xu Jinghang, Yang Song, Han Yifan, Jia Jidong, Nan Yuemin, Wei Lai, Duan Zhongping, Zhuang Hui

机构信息

Department of Gastroenterology, Peking University First Hospital, Beijing, China.

Center for Liver Diseases, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.

出版信息

J Clin Transl Hepatol. 2025 Jun 28;13(6):516-523. doi: 10.14218/JCTH.2025.00105. Epub 2025 Apr 24.

DOI:10.14218/JCTH.2025.00105
PMID:40474886
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12134906/
Abstract

Thrombocytopenia in cirrhosis presents significant challenges in clinical practice. To help clinicians rapidly understand and standardize the diagnosis and treatment of this condition, the Liver Fibrosis, Cirrhosis, and Portal Hypertension Group under the Chinese Society of Hepatology, Chinese Medical Association, convened experts across relevant fields to formulate the . This consensus aimed to provide evidence-based guidance for clinical diagnosis and treatment.

摘要

肝硬化中的血小板减少症在临床实践中带来了重大挑战。为帮助临床医生快速了解并规范这种病症的诊断和治疗,中华医学会肝病学分会肝纤维化、肝硬化和门静脉高压症学组召集了相关领域的专家制定了《……》。这一共识旨在为临床诊断和治疗提供循证指导。

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Chinese Expert Consensus for the Management of Thrombocytopenia in Cirrhosis.肝硬化血小板减少症管理的中国专家共识
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2
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本文引用的文献

1
[An analysis of related factors in thrombocytopenia combined with cirrhosis: a cross-sectional study of 2 517 cases].血小板减少症合并肝硬化相关因素分析:2517例横断面研究
Zhonghua Gan Zang Bing Za Zhi. 2024 Jun 20;32(6):508-516. doi: 10.3760/cma.j.cn501113-20240408-00183.
2
[Chinese expert consensus on the clinical management of liver disease-associated thrombocytopenia syndrome].[肝病相关性血小板减少综合征临床管理中国专家共识]
Zhonghua Gan Zang Bing Za Zhi. 2023 Nov 20;31(11):1137-1148. doi: 10.3760/cma.j.cn501113-20230925-00120.
3
Safety and effectiveness of lusutrombopag in patients who have chronic liver disease with thrombocytopenia and undergoing invasive procedures: Real-world post-marketing surveillance in Japan.芦曲泊帕在患有慢性肝病伴血小板减少症且正在接受侵入性操作的患者中的安全性和有效性:日本的真实世界上市后监测
Hepatol Res. 2023 Nov;53(11):1105-1116. doi: 10.1111/hepr.13945. Epub 2023 Aug 11.
4
Minimum platelet count threshold before invasive procedures in cirrhosis: Evolution of the guidelines.肝硬化患者侵入性操作前的最低血小板计数阈值:指南的演变
World J Gastrointest Surg. 2023 Feb 27;15(2):127-141. doi: 10.4240/wjgs.v15.i2.127.
5
Periprocedural management of hemostatic alterations in patients with cirrhosis and vascular liver disorders: a step forward of the American Association for the Study of Liver Diseases.肝硬化和肝脏血管疾病患者围手术期止血改变的管理:美国肝病研究协会的一项进展
Hepatobiliary Surg Nutr. 2023 Feb 28;12(1):105-109. doi: 10.21037/hbsn-22-556. Epub 2023 Jan 16.
6
An-Luo-Hua-Xian Pill Improves the Regression of Liver Fibrosis in Chronic Hepatitis B Patients Treated with Entecavir.安络化纤丸改善恩替卡韦治疗的慢性乙型肝炎患者肝纤维化的消退情况。
J Clin Transl Hepatol. 2023 Apr 28;11(2):304-313. doi: 10.14218/JCTH.2022.00091. Epub 2022 Jun 6.
7
Recombinant human thrombopoietin treatment in patients with chronic liver disease-related thrombocytopenia undergoing invasive procedures: A retrospective study.重组人血小板生成素治疗慢性肝病相关性血小板减少症患者行侵入性操作:一项回顾性研究。
World J Gastrointest Surg. 2022 Nov 27;14(11):1260-1271. doi: 10.4240/wjgs.v14.i11.1260.
8
Efficacy and safety of heparin plus dexamethasone after partial splenic embolization for liver cirrhosis with massive splenomegaly.肝素联合地塞米松在部分性脾动脉栓塞术治疗肝硬化巨脾中的疗效及安全性。
BMC Gastroenterol. 2022 Nov 19;22(1):470. doi: 10.1186/s12876-022-02580-8.
9
EHA Guidelines on Management of Antithrombotic Treatments in Thrombocytopenic Patients With Cancer.欧洲血液学协会癌症血小板减少患者抗血栓治疗管理指南
Hemasphere. 2022 Jul 13;6(8):e750. doi: 10.1097/HS9.0000000000000750. eCollection 2022 Aug.
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Haemostatic alterations and management of haemostasis in patients with cirrhosis.肝硬化患者的止血异常及止血管理。
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