Dudley D K, Black D M
Obstet Gynecol. 1985 Oct;66(4):521-4.
Diabetic pregnancy is said to be associated with a delay in pulmonary maturity and significant false-positive rates for the lecithin/sphingomyelin (L:S) ratio. Lecithin/sphingomyelin ratios without routine estimation of phosphatidylglycerol in the management of 102 insulin-dependent diabetics were analyzed to assess whether or not these ratios were mature at 37 weeks and whether or not the method used was reliable. Only two of 102 (1.9%) values were reported at less than 2 to 1 from amniocentesis at 37 weeks' gestation. The incidence of respiratory distress syndrome was zero. The authors concluded that the L:S ratio measured by the method used, is a reliable predictor of lung maturity in diabetic pregnancy and that with strict glucose homeostasis, normal pulmonary maturation occurs by 37 weeks' gestation in diabetic pregnancy.
糖尿病妊娠被认为与肺成熟延迟以及卵磷脂/鞘磷脂（L:S）比值出现显著假阳性率有关。对102例胰岛素依赖型糖尿病患者在管理过程中未常规评估磷脂酰甘油时的卵磷脂/鞘磷脂比值进行分析，以评估这些比值在孕37周时是否成熟以及所采用的方法是否可靠。在妊娠37周时进行羊膜穿刺术，102个值中只有2个（1.9%）报告小于2:1。呼吸窘迫综合征的发生率为零。作者得出结论，采用的方法所测得的L:S比值是糖尿病妊娠肺成熟的可靠预测指标，并且通过严格控制血糖稳态，糖尿病妊娠在孕37周时可实现正常的肺成熟。
