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糖尿病酮症酸中毒患者的鼻眶脑毛霉菌病:塞内加尔仍不为人知的典型临床表现

Rhino-orbital-cerebral mucormycosis in diabetic ketoacidosis: A classic clinical presentation still unknown in Senegal.

作者信息

Diongue Khadim, Daffé Sokhna Moumi, Sané Abdourakhmane, Ndoye Maguette, Gueye Mamadou Wagué, Ngom Mor, Diawara Papa Silman, Ranque Stéphane, Fall Bécaye

机构信息

Laboratory of Parasitology and Mycology, Aristide Le Dantec University Hospital, 30 Avenue Pasteur, Dakar 12900, Senegal.

Laboratory of Medical Biology, Hôpital Principal de Dakar, Route de la Corniche Estate, Dakar 12900, Senegal.

出版信息

IDCases. 2025 May 4;40:e02244. doi: 10.1016/j.idcr.2025.e02244. eCollection 2025.

Abstract

Rhino-orbital-cerebral mucormycosis (ROCM) is an invasive mycosis caused by fungi of the order Mucorales. It mainly affects patients with uncontrolled diabetes. This case report concerns a 27-year-old woman with diabetic ketoacidosis who presented with a large erythematous plaque localised in the right orbitofrontal region with exophthalmos and patches of necrosis that rapidly led to death within 3 days before the diagnosis of ROCM due to , the causal agent. So, without rapid diagnosis and swift management, ROCM results in a potential fatality.

摘要

鼻眶脑毛霉菌病(ROCM)是一种由毛霉目真菌引起的侵袭性真菌病。它主要影响糖尿病控制不佳的患者。本病例报告涉及一名27岁患有糖尿病酮症酸中毒的女性,她在右眶额区域出现一个大的红斑性斑块,伴有眼球突出和坏死斑,在诊断出由 (病原体)引起的ROCM之前3天内迅速死亡。因此,若无快速诊断和迅速治疗,ROCM会导致潜在的死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8657/12138463/ea19f8af889a/gr1.jpg

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