革兰阴性菌血流感染治疗疗程的变异性及与疗程延长相关的因素。
Variability in Durations of Therapy for Gram-Negative Bloodstream Infections and Factors Associated With Prolonged Durations.
作者信息
Sutton Jesse D, Lee Jae Hyoung, Howard Karen, Quartuccio Katelyn S, McCoy Christopher, Gupta Alok, Slish Judianne C, Engers Drew W, Malani Anurag N, Karaba Sara M, Pillinger Kelly E, Tamma Pranita D, Jenkins Timothy C
机构信息
Department of Pharmacy, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah, USA.
Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
出版信息
Open Forum Infect Dis. 2025 May 15;12(6):ofaf298. doi: 10.1093/ofid/ofaf298. eCollection 2025 Jun.
Data on treatment durations for gram-negative bloodstream infections in clinical practice are limited. In this study of 4240 gram-negative bloodstream infection episodes during 2019 from 24 US hospitals, the median duration of therapy was 12 days (IQR, 9-15); 59% were treated for >10 days. There was marked variability in treatment durations across hospitals.
临床实践中关于革兰氏阴性菌血流感染治疗疗程的数据有限。在这项对2019年美国24家医院的4240例革兰氏阴性菌血流感染病例的研究中，治疗疗程的中位数为12天（四分位间距，9 - 15天）；59%的患者接受了超过10天的治疗。不同医院之间的治疗疗程存在显著差异。
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