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贝那利珠单抗治疗与慢性嗜酸性粒细胞性肺炎三维支气管树变化

Benralizumab treatment and 3-dimensional bronchial tree changes in chronic eosinophilic pneumonia.

作者信息

Kai Yoshiro, Hishida Yuichi

机构信息

Department of Respiratory Medicine, Minami-Nara General Medical Center, Nara, Japan.

Department of Respiratory Medicine, Nara Medical University, Nara, Japan.

出版信息

J Allergy Clin Immunol Glob. 2025 Apr 25;4(3):100490. doi: 10.1016/j.jacig.2025.100490. eCollection 2025 Aug.

Abstract

Patients with chronic eosinophilic pneumonia often experience recurring disease and prolonged corticosteroid use with adverse effects. Benralizumab enabled corticosteroid discontinuation and successfully treated chronic eosinophilic pneumonia in our study, confirmed through remission induction therapy and 3-dimensional bronchial tree visualization.

摘要

慢性嗜酸性粒细胞性肺炎患者常经历疾病复发以及长期使用皮质类固醇带来的不良反应。在我们的研究中,贝那利珠单抗能够停用皮质类固醇,并成功治疗慢性嗜酸性粒细胞性肺炎,这通过诱导缓解疗法和三维支气管树可视化得到证实。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab90/12139403/5be1a0be6424/gr1.jpg

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