Akhtar Ujala, Naeem Hamid, Fida Sanam, Akhtar Saddaf, Yousuf Ihtesham, Zia Ayesha
Medicine, Khyber Teaching Hospital (KTH), Peshawar, PAK.
Cardiac ICU, Rehman Medical Institute (RMI), Peshawar, PAK.
Cureus. 2025 May 6;17(5):e83583. doi: 10.7759/cureus.83583. eCollection 2025 May.
Atrial fibrillation (AF) is a common complication following coronary artery bypass grafting (CABG) and is associated with increased morbidity and prolonged hospital stay. This study aimed to determine the frequency of new-onset atrial fibrillation (NOAF) in post-CABG patients and assess its association with demographic and clinical variables, including comorbidities.
This descriptive observational study was conducted in the Cardiac ICU of Rehman Medical Institute (RMI) over six months. A total of 101 post-CABG patients admitted to the ICU were included and monitored for the development of AF. Patients with congenital anomalies, a prior history of arrhythmias, or those who did not provide consent were excluded. Data were collected prospectively, including patient demographics, comorbidities, and antiarrhythmic management. Statistical analysis was performed using SPSS version 26 (Armonk, NY: IBM Corp.), with quantitative variables presented as means±standard deviations and qualitative variables as frequencies and percentages.
The frequency of NOAF in post-CABG patients was found to be 13.86% (n=14). The mean age of the study population was 59.62 years (SD=9.81), with a male predominance (69 males, 32 females). Hypertension (HTN) and coronary artery disease (CAD) were the most common comorbidities, affecting 29.7% (n=30) and 20.8% (n=21) of patients, respectively. A trend was observed suggesting that patients with multiple comorbidities had an increased likelihood of developing AF, although this finding was descriptive and not statistically significant. Antiarrhythmic medications were administered in all AF cases, with a variable response.
The incidence of NOAF in post-CABG patients remains significant based on previous researches. Age and pre-existing comorbidities, particularly hypertension and CAD, appear to contribute to AF development. Developing preoperative and intraoperative risk assessment tools may help identify patients at higher risk for post-CABG atrial fibrillation. Future interventional studies can evaluate strategies such as fluid management, early beta-blockers, or anti-inflammatory therapies to reduce the incidence of AF.
心房颤动(AF)是冠状动脉旁路移植术(CABG)后常见的并发症,与发病率增加和住院时间延长相关。本研究旨在确定冠状动脉旁路移植术后患者新发心房颤动(NOAF)的发生率,并评估其与人口统计学和临床变量(包括合并症)的关联。
这项描述性观察性研究在雷曼医学院(RMI)心脏重症监护病房进行,为期六个月。共有101名入住重症监护病房的冠状动脉旁路移植术后患者被纳入研究,并监测房颤的发生情况。排除患有先天性异常、既往有心律失常病史或未提供同意书的患者。前瞻性收集数据,包括患者人口统计学、合并症和抗心律失常治疗情况。使用SPSS 26版(纽约州阿蒙克:IBM公司)进行统计分析,定量变量以均值±标准差表示,定性变量以频率和百分比表示。
冠状动脉旁路移植术后患者中NOAF的发生率为13.86%(n = 14)。研究人群的平均年龄为59.62岁(SD = 9.81),男性占主导(69名男性,32名女性)。高血压(HTN)和冠状动脉疾病(CAD)是最常见的合并症,分别影响29.7%(n = 30)和20.8%(n = 21)的患者。观察到一种趋势,提示合并多种合并症的患者发生房颤的可能性增加,尽管这一发现具有描述性且无统计学意义。所有房颤病例均给予了抗心律失常药物治疗,反应各异。
根据以往研究,冠状动脉旁路移植术后患者中NOAF的发生率仍然较高。年龄和既往合并症,特别是高血压和CAD,似乎与房颤的发生有关。开发术前和术中风险评估工具可能有助于识别冠状动脉旁路移植术后房颤风险较高的患者。未来的干预性研究可以评估诸如液体管理策略、早期使用β受体阻滞剂或抗炎治疗等措施,以降低房颤的发生率。