Chung Pooi Yin
J Glob Health. 2025 Jun 6;15:03025. doi: 10.7189/jogh.15.03025.
Antimicrobial resistance (AMR) is a multifactorial global public health concern that is interlinked with the health of humans, animals, and the environment. Therapeutically important antibiotics used widely in the mass medication of livestock have contributed significantly to AMR, as they eventually enter the environment due to inadequate treatment of wastewater. Similarly, improper discharge of antibiotic-contaminated waste by the medical sector exacerbates the problem by contributing to the increase in the selection of resistant bacteria and the horizontal transfer of resistance genes. Developed and developing countries and regions worldwide acknowledged that no discipline or sector of society can successfully address climate change, known and emerging infectious diseases, and AMR by acting in isolation. Countries in Southeast Asia, like elsewhere in the world, have also adopted a transdisciplinary and multi-sectoral collaboration integrating human, animal, and environmental health, known as the One Health strategy.
抗菌药物耐药性（AMR）是一个多因素的全球公共卫生问题，与人类、动物和环境的健康相互关联。广泛用于牲畜群体用药的具有治疗重要性的抗生素对AMR有重大影响，因为由于废水处理不当，它们最终会进入环境。同样，医疗部门对抗生素污染废物的不当排放，通过增加耐药菌的选择和耐药基因的水平转移，加剧了这一问题。全球的发达国家和发展中国家及地区都认识到，社会的任何学科或部门都无法孤立地成功应对气候变化、已知和新出现的传染病以及AMR。与世界其他地方一样，东南亚国家也采用了将人类、动物和环境卫生整合在一起的跨学科和多部门合作，即“同一健康”战略。
