严重急性呼吸综合征冠状病毒2(SARS-CoV-2)传播概述及降低风险的工程策略。

An overview of SARS-CoV-2 transmission and engineering strategies to mitigate risk.

作者信息

Leo Bey Fen, Lin Chin Yik, Markandan Kalaimani, Saw Lip Huat, Mohd Nadzir Mohd Shahrul, Govindaraju Kayatri, Shariffuddin Ina Ismiarti, Sankara Revathy, Tiong Yong Wei, Pakalapati Harshini, Khalid Mohammad

机构信息

Department of Molecular Medicine, Faculty of Medicine, Universiti Malaya, 50603, Kuala, Lumpur, Malaysia.

Department of Geology, Faculty of Science, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.

出版信息

J Build Eng. 2023 Aug 15;73:106737. doi: 10.1016/j.jobe.2023.106737. Epub 2023 May 8.

Abstract

The spread of the COVID-19 pandemic has profoundly affected every aspect of our lives. To date, experts have acknowledged that airborne transmission is a key piece of the SARS-CoV-2 puzzle. Nevertheless, the exact mechanism of airborne transmission of SARS-CoV-2 remains unclear. Recent works have shown the spreading of SARS-CoV-2 through numerical modeling and experimental works, but the successful applications of engineering approaches in reducing the spread of SARS-CoV-2 are lacking. In this review, the environmental factors that influence the transmission risk of SARS-CoV-2, such as ventilation flow rates, humidity, and temperature, are discussed. Besides, additional macro and micro weather factors, regional and global transmission, and the variants of the spread of SARS-CoV-2 are also reviewed. Engineering approaches that practically reduce the risks of SARS-CoV-2 transmissions are reported. Given the complex human behavior, environmental properties, and dynamic nature of the SARS-CoV-2 virus, it is reasonable to summarize that SARS-CoV-2 may not be eradicated even with the timely implementation of interventions. Therefore, more research exploring the potential cost-effective ways to control the transmission rate of SARS-CoV-2 may be a worthwhile pursuit to moderate the current crisis.

摘要

新冠疫情的蔓延已深刻影响到我们生活的方方面面。迄今为止,专家们已承认空气传播是新冠病毒传播难题的关键一环。然而,新冠病毒空气传播的确切机制仍不明确。近期的研究通过数值模拟和实验展示了新冠病毒的传播情况,但在运用工程方法降低新冠病毒传播方面仍缺乏成功案例。在这篇综述中,我们讨论了影响新冠病毒传播风险的环境因素,如通风流量、湿度和温度。此外,还综述了其他宏观和微观气象因素、区域和全球传播以及新冠病毒传播的变异情况。报告了切实降低新冠病毒传播风险的工程方法。鉴于人类行为的复杂性、环境特性以及新冠病毒的动态性质,即使及时实施干预措施,新冠病毒也可能无法根除,这是合理的推断。因此,开展更多研究以探索控制新冠病毒传播率的潜在性价比高的方法,可能是缓解当前危机的一项值得追求的工作。

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