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用某些降糖药治疗前后四氧嘧啶糖尿病患者的血清矿物质变化

Serum mineral changes in alloxan diabetes before and after treatment with some hypoglycemic drugs.

作者信息

Halim D, Khalifa K, Awadalah R, El-Dessoukey E A, Hafez T, El-Hawary Z

出版信息

Z Ernahrungswiss. 1977 Mar;16(1):39-43. doi: 10.1007/BF02021210.

DOI:10.1007/BF02021210
PMID:404772
Abstract

In alloxan diabetes, serum zinc, copper, iron and magnesium were significantly higher than in normal rats, while the level of serum calcium, sodium, and potassium was lower than normal. Treatment with daonil or insulin led to a normalization, as expected of the level of serum glucose and most of the other elements, except for iron and potassium. When lycanol was used for treatment, the level of all elements returned to the normal except for blood glucose, zinc and potassium.

摘要

在四氧嘧啶糖尿病大鼠中,血清锌、铜、铁和镁显著高于正常大鼠,而血清钙、钠和钾水平低于正常。如预期的那样,用达诺林或胰岛素治疗可使血清葡萄糖和大多数其他元素的水平恢复正常,但铁和钾除外。当使用狼毒素进行治疗时,除血糖、锌和钾外,所有元素的水平均恢复正常。

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引用本文的文献

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本文引用的文献

1
[Relation between insulin and zinc in the islands of Langerhans, with special reference to blood sugar control and insulin secretion].[胰岛中胰岛素与锌的关系,特别涉及血糖控制和胰岛素分泌]
Experientia. 1955 Mar 15;11(3):122-8. doi: 10.1007/BF02161704.
2
[EFFECT OF ADRENALIN AND CORTISONE ON THE BLOOD SERUM TRACE ELEMENT CONTENT].[肾上腺素和可的松对血清微量元素含量的影响]
Ukr Biokhim Zh. 1964;36:506-12.
3
THE ANALYSIS OF BIOLOGICAL MATERIALS BY ATOMIC-ABSORPTION SPECTROSCOPY.用原子吸收光谱法分析生物材料
某些降糖药物治疗前后实验性糖尿病血清酶的变化
Z Ernahrungswiss. 1977 Dec;16(4):235-40. doi: 10.1007/BF02023702.
Clin Chem. 1965 Feb;11:SUPPL:251-8.
4
[Forms of calcium in tissues].[组织中的钙形式]
Vopr Med Khim. 1959 Mar-Apr;5(2):112-3.
5
[Mechanism of the hypothermic action of insulin: hypoglycemia and disequilibrium of the plasma ions].[胰岛素低温作用的机制:低血糖与血浆离子失衡]
C R Hebd Seances Acad Sci. 1959 Jan 26;248(4):595-7.
6
[Combined effect of insulin and glucose on plasma magnesium in dogs].[胰岛素和葡萄糖对犬血浆镁的联合作用]
C R Seances Soc Biol Fil. 1958;152(3):487-9.
7
Serum magnesium and other electrolytes in insulin-induced hypoglycemia.胰岛素诱导低血糖症中的血清镁及其他电解质
Am J Psychiatry. 1956 Jun;112(12):1024-5. doi: 10.1176/ajp.112.12.1024.
8
Mechanisms of insulin and epinephrine effect on the level of plasma potassium.胰岛素和肾上腺素对血浆钾水平影响的机制。
Endocrinology. 1953 Nov;53(5):564-71. doi: 10.1210/endo-53-5-564.
9
[Zinc metabolism in alloxan diabetes].[四氧嘧啶糖尿病中的锌代谢]
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1952 Oct 10;216(5):457-72.
10
On the development of alloxan diabetes in mice.关于小鼠四氧嘧啶糖尿病的发展
Eur J Pharmacol. 1967 Oct;2(1):35-41. doi: 10.1016/0014-2999(67)90020-9.