Suppr超能文献

一名长期使用托法替布治疗且近期感染新型冠状病毒肺炎的类风湿关节炎患者的D-二聚体变化趋势

d-Dimer trend in a long-term rheumatoid arthritis patient with tofacitinib treatment and recent COVID-19 infection.

作者信息

Maldonado Genessis, Guerrero Roberto, Intriago Maria, Rios Carlos

机构信息

Internal Medicine Residency Program, Loyola MacNeal Hospital, Berwyn, IL, USA.

Rheumatology Department, School of Medicine, Universidad Espiritu Santo, Guayaquil, Ecuador.

出版信息

Rev Colomb Reumatol. 2022 Jun;29:S84-S87. doi: 10.1016/j.rcreu.2021.06.003. Epub 2021 Jul 5.

Abstract

The SARS-CoV-2 virus was first identified in December 2019, the infection was named COVID-19. The initial symptoms and evolution of the disease have been described over the past year. The virus has been shown to increase the risk of thromboembolic events due to the hypercoagulable state triggered by systemic endothelial inflammation. We present the case of a patient with a history of rheumatoid arthritis under prolonged treatment with tofacitinib, who presented COVID-19 and subsequently developed a hypercoagulable state of approximately 6 months' duration. The possible association between viral infection and the use of tofacitinib is debated.

摘要

严重急性呼吸综合征冠状病毒2(SARS-CoV-2)于2019年12月首次被发现,该感染被命名为2019冠状病毒病(COVID-19)。在过去一年中已经描述了该疾病的初始症状和演变过程。由于全身性内皮炎症引发的高凝状态,已表明该病毒会增加血栓栓塞事件的风险。我们报告一例有类风湿关节炎病史且长期接受托法替布治疗的患者,该患者感染了COVID-19,随后出现了持续约6个月的高凝状态。病毒感染与托法替布使用之间的可能关联存在争议。

相似文献

本文引用的文献

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验