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新生儿黄疸的家庭光疗治疗

Home phototherapy treatment of neonatal jaundice.

作者信息

Eggert L D, Pollary R A, Folland D S, Jung A L

出版信息

Pediatrics. 1985 Oct;76(4):579-84.

PMID:4047802
Abstract

A home phototherapy program for healthy, term newborns with hyperbilirubinemia (n = 62) was implemented, and results were compared prospectively with a group of term neonates who met enrollment criteria but were treated in-hospital (n = 55). The purpose of the study was to prospectively assess the feasibility, safety, and effectiveness of home phototherapy in treating uncomplicated neonatal jaundice. Infants were required to be greater than 24 hours old and to weigh at least 2,270 g (5 lb). Enrolling physicians were instructed to select infants whose clinical diagnoses and bilirubin levels allowed an adequate margin of error for a trial of home phototherapy and whose parents were capable of managing the added responsibilities of home therapy. At the time the phototherapy equipment was delivered and set up in their home, parents received extensive instruction, including how to record pertinent ongoing data on a home flow sheet. Serum bilirubin levels were measured at least daily. The preponderant diagnosis listed by enrolling physicians was "physiologic jaundice." No parent reported significant complications, and no infant required rehospitalization. Bilirubin levels decreased as rapidly in the home group as in the hospitalized control group, and duration of treatment averaged 2.8 days. About $18,000 was saved by treating these 62 infants at home compared with in-hospital costs in our community. We found home phototherapy to be a feasible, safe, and effective alternative to in-hospital phototherapy for otherwise healthy, jaundiced infants with motivated and capable parents.

摘要

针对62名患有高胆红素血症的足月健康新生儿实施了一项家庭光疗计划,并将结果与一组符合入选标准但在医院接受治疗的足月新生儿(n = 55)进行了前瞻性比较。该研究的目的是前瞻性评估家庭光疗治疗单纯性新生儿黄疸的可行性、安全性和有效性。婴儿需大于24小时且体重至少2270克(5磅)。指导参与登记的医生选择临床诊断和胆红素水平允许在家庭光疗试验中有足够误差范围且其父母能够承担家庭治疗额外责任的婴儿。在光疗设备送达并在其家中安装时,父母接受了广泛的指导,包括如何在家庭记录表上记录相关的持续数据。血清胆红素水平至少每天测量一次。参与登记的医生列出的主要诊断为“生理性黄疸”。没有家长报告重大并发症,也没有婴儿需要再次住院。家庭组的胆红素水平下降速度与住院对照组一样快,平均治疗持续时间为2.8天。与在我们社区医院治疗相比,在家中治疗这62名婴儿节省了约18000美元。我们发现,对于有积极性且有能力的父母所生的健康黄疸婴儿,家庭光疗是医院光疗的一种可行、安全且有效的替代方法。

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