Kim Sangwan, Choo Eunjung, Jang Eun Jin, Je Nam Kyung, Lee Iyn-Hyang
Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
College of Pharmacy, Ajou University, Suwon, Republic of Korea.
PLoS One. 2025 Jun 6;20(6):e0325553. doi: 10.1371/journal.pone.0325553. eCollection 2025.
Hospitalization often indicates deteriorating health, longer treatment times, and higher healthcare costs. This study aimed to investigate associations between continuity of care (COC) and asthma-related hospitalizations using a rigorous methodology.
This retrospective cohort study was conducted using national health insurance claims data. The study included adults with a diagnosis of asthma between 2015 and 2016 in a primary care setting. The exposure was measured using continuity of care indices (COCIs) during the first two years after inclusion. Cohorts were categorized into two groups based on COCI levels. The primary outcome was the incidence of asthma-related hospitalizations, and the secondary outcomes were emergency department (ED) utilization, systemic corticosteroid use, and asthma-related medical costs.
A total of 24,173 patients were eligible for analysis, 13,212 of whom were continuously cared for by primary doctors (the continuity group), and 10,961 non-continuously (the non-continuity group). During a 2 year-follow-up period, 230 patients (1.74%) were hospitalized in the continuity group and 404 (3.69%) in the non-continuity group. After adjusting for confounding covariates, patients in the non-continuity group were found to be at significantly higher risk of hospital admission (adjusted hazard ratio (aHR)=2.04 [95% confidence interval = 1.73 ~ 2.41]). In addition, the risk of ED visits, systemic corticosteroid use, and costs were higher for patients in the non-continuity group (aHR = 2.26 [1.32 ~ 3.87], adjusted OR=1.58 [1.35 ~ 1.82], and expβ = 1.41 [1.37 ~ 1.45], respectively).
In adult asthma patients at the early stages of illness, increased continuity of primary care was found to be associated with fewer hospitalizations, fewer ED visits, and lower healthcare expenditures.
住院治疗往往意味着健康状况恶化、治疗时间延长和医疗成本增加。本研究旨在采用严谨的方法调查医疗连续性(COC)与哮喘相关住院治疗之间的关联。
本回顾性队列研究使用了国家医疗保险理赔数据。该研究纳入了2015年至2016年在初级医疗环境中被诊断为哮喘的成年人。在纳入后的头两年,使用医疗连续性指数(COCI)来衡量暴露情况。根据COCI水平将队列分为两组。主要结局是哮喘相关住院治疗的发生率,次要结局是急诊科(ED)就诊率、全身使用皮质类固醇的情况以及哮喘相关医疗费用。
共有24,173名患者符合分析条件,其中13,212名由初级医生持续护理(连续性组),10,961名未得到持续护理(非连续性组)。在为期2年的随访期内,连续性组有230名患者(1.74%)住院,非连续性组有404名患者(3.69%)住院。在对混杂协变量进行调整后,发现非连续性组患者的住院风险显著更高(调整后风险比(aHR)=2.04 [95%置信区间=1.73~2.41])。此外,非连续性组患者的急诊科就诊风险、全身使用皮质类固醇的风险和费用也更高(分别为aHR = 2.26 [1.32~3.87],调整后比值比=1.58 [1.35~1.82],以及指数β = 1.41 [1.37~1.4])。
在疾病早期的成年哮喘患者中,发现初级医疗连续性的提高与住院次数减少、急诊科就诊次数减少以及医疗支出降低有关。