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老年人腹股沟疝、股疝和腹疝的全球负担及未来趋势:来自《2021年全球疾病负担研究》的系统分析

Global burden and future trends of inguinal, femoral, and abdominal hernia in older adults: A systematic analysis from the Global Burden of Disease Study 2021.

作者信息

Zhang Jinwei, Wang Jiaxuan, Han Xiangyu, Fan Junjie, Huang Chao, Dong Yonghong

机构信息

The Gastrointestinal, Pancreatic, Hernia and Abdominal Wall Surgery Department of, Shanxi Provincial People's Hospital, Shanxi Medical University, Taiyuan, China.

The Fifth Clinical Medical College, Shanxi Medical University, Taiyuan, China.

出版信息

PLoS One. 2025 Jun 6;20(6):e0323790. doi: 10.1371/journal.pone.0323790. eCollection 2025.


DOI:10.1371/journal.pone.0323790
PMID:40478891
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12143580/
Abstract

OBJECTIVE: This study aims to comprehensively evaluate the global, regional, and national burden, trends, and health inequalities of inguinal, femoral, and abdominal hernias among older adults from 1990 to 2021, conduct predictive analyses, and provide insights to inform future public health strategies. METHODS: A secondary analysis was conducted using the Global Burden of Disease 2021, focusing on the temporal trends, health inequality, and predictive development of inguinal, femoral, and abdominal hernia burden among older adults. RESULTS: Globally, the number of incident cases of inguinal, femoral, and abdominal hernias among older adults continuously increased from 1990 to 2021, along with the decline in age-standardized rates, prevalence, and Disability-Adjusted Life Years (DALYs). Older males exhibited higher incidence rates, prevalence, and DALYs for hernias relative to females. In terms of the Socio-Demographic Index (SDI) from 1990 to 2021, the Age-Standardized Prevalence Rate (ASPR) and Age-Standardized Rate of Disability-Adjusted Life Years (ASDR) remained the highest in low-middle and low SDI regions, while the Age-Standardized Incidence Rate (ASIR) was the highest in high SDI regions. At the national level, 10 countries experienced a significant increase in ASDR and ASPR, and 15 countries in ASIR. Among these, the highest increase was observed for ASIR in China, ASPR in Georgia, and ASDR in American Samoa. The projections to the year 2035 indicate an increase in the incidence and prevalence of hernias, with older males remaining predominant. However, the DALY rate is expected a declining trend. CONCLUSIONS: In spite of the progress in reducing the burden of inguinal, femoral, and abdominal hernias in older adults, the overall burden tends to rise. In particular, countries such as India, China, and Georgia are experiencing an increasing burden. It is crucial to implement targeted medical interventions, especially for older males in these regions.

摘要

目的:本研究旨在全面评估1990年至2021年期间老年人腹股沟疝、股疝和腹疝的全球、区域和国家负担、趋势及健康不平等情况,进行预测分析,并提供见解以指导未来的公共卫生策略。 方法:利用《2021年全球疾病负担》进行二次分析,重点关注老年人腹股沟疝、股疝和腹疝负担的时间趋势、健康不平等及预测发展情况。 结果:在全球范围内,1990年至2021年期间老年人腹股沟疝、股疝和腹疝的新发病例数持续增加,同时年龄标准化发病率、患病率和伤残调整生命年(DALYs)有所下降。老年男性的疝发病率、患病率和DALYs高于女性。就1990年至2021年的社会人口指数(SDI)而言,年龄标准化患病率(ASPR)和年龄标准化伤残调整生命年率(ASDR)在中低收入和低SDI地区仍然最高,而年龄标准化发病率(ASIR)在高SDI地区最高。在国家层面,10个国家的ASDR和ASPR显著增加,15个国家的ASIR显著增加。其中,中国的ASIR、格鲁吉亚的ASPR和美属萨摩亚的ASDR增幅最大。到2035年的预测表明,疝的发病率和患病率将增加,老年男性仍然占主导地位。然而,DALY率预计呈下降趋势。 结论:尽管在减轻老年人腹股沟疝、股疝和腹疝负担方面取得了进展,但总体负担仍呈上升趋势。特别是印度、中国和格鲁吉亚等国家的负担正在增加。实施有针对性的医疗干预措施至关重要,尤其是针对这些地区的老年男性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d273/12143580/97807b11ff99/pone.0323790.g008.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d273/12143580/acdb4947ff6b/pone.0323790.g007.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d273/12143580/fb9115898cc7/pone.0323790.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d273/12143580/0e2aa0b0b855/pone.0323790.g002.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d273/12143580/97807b11ff99/pone.0323790.g008.jpg

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