Kim Jongmin J
Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.
Mol Cell. 2025 Jun 5;85(11):2061-2063. doi: 10.1016/j.molcel.2025.05.016.
In this issue, Lagan et al. apply genome-wide and tiling-scan CRISPR screens to uncover a key role for CBX4 and its central region in promoting the growth of diffuse midline glioma cells bearing the H3K27M mutation.
在本期杂志中,拉根等人应用全基因组和平铺扫描CRISPR筛选技术,以揭示CBX4及其中心区域在促进携带H3K27M突变的弥漫性中线胶质瘤细胞生长中的关键作用。