Fang Jonathan X, Villablanca Pedro A
Center for Structural Heart Disease, Henry Ford Health System, Detroit, Michigan, USA; National Heart Centre Singapore, Singapore.
Center for Structural Heart Disease, Henry Ford Health System, Detroit, Michigan, USA.
JACC Case Rep. 2025 Jun 4;30(13):103912. doi: 10.1016/j.jaccas.2025.103912.
Bioprosthetic or native Aortic Scallop Intentional Laceration to prevent Iatrogenic Coronary Artery obstruction (BASILICA) is currently the standard technique for leaflet modification in transcatheter aortic valve replacement to overcome coronary obstruction. The technique involves traversal of the coronary cusp with a 0.014-inch coronary wire, snaring the wire, and then lacerating the leaflet with a denuded portion of the wire known as the flying V. The procedure requires careful planning and technical expertise. We report a new complication of BASILICA where prepositioning of a transcatheter heart valve (THV) before laceration accidentally damaged the THV.
This complication originates from the inadvertent crossing of the straight-tip wire between the flying V and the aortic cusp when the flying V was not well apposed to the cusp. Prepositioning of the THV has become a variation of the procedure for patients with a high perceived risk of hemodynamic instability after BASILICA. This backfired, resulting in a complicated procedure.
The exact position of the 0.014-inch wire and flying V might be difficult to visualize in patients with a large body habitus. Operators should check that the flying V is at the cusp level before crossing the aortic valve with a wire. During the initial delivery of the flying V to the cusp, care should be taken to avoid losing the wire in the guide. Multicenter data of BASILICA show that hemodynamic instability is uncommon in single-leaflet lacerations. Therefore, prepositioning of a THV before leaflet laceration is usually unnecessary and requires strong clinical justification if pursued TAKE-HOME MESSAGES: BASILICA is a complex procedure. Operator familiarity with potential pitfalls and appropriate bailout methods are necessary. Operators should ensure that the flying V is well apposed to the leaflet before crossing into the left ventricle with a wire to prepare for valve deployment.
生物假体或天然主动脉瓣叶故意撕裂以预防医源性冠状动脉阻塞(BASILICA)目前是经导管主动脉瓣置换术中用于克服冠状动脉阻塞的瓣叶改良标准技术。该技术包括用0.014英寸的冠状动脉导丝穿过冠状动脉瓣叶,套住导丝,然后用导丝的裸露部分(即“飞行V”)撕裂瓣叶。该操作需要仔细规划和技术专长。我们报告了BASILICA的一种新并发症,即撕裂前经导管心脏瓣膜(THV)的预定位意外损坏了THV。
当“飞行V”未很好地贴合瓣叶时,直头导丝在“飞行V”和主动脉瓣叶之间意外穿过,导致了这一并发症。对于BASILICA术后血流动力学不稳定风险较高的患者,THV预定位已成为该手术的一种变体。但事与愿违,导致了手术复杂化。
对于体型较大的患者,0.014英寸导丝和“飞行V”的确切位置可能难以看清。术者在用导丝穿过主动脉瓣之前应检查“飞行V”是否处于瓣叶水平。在将“飞行V”首次送至瓣叶时,应注意避免导丝在导管内丢失。BASILICA的多中心数据显示,单瓣叶撕裂时血流动力学不稳定并不常见。因此,通常无需在瓣叶撕裂前进行THV预定位,若要进行则需要有充分的临床理由。
BASILICA是一个复杂的手术。术者需熟悉潜在陷阱和合适的补救方法。在用导丝进入左心室准备部署瓣膜之前,术者应确保“飞行V”与瓣叶良好贴合。