Sokol A F
Probl Endokrinol (Mosk). 1985 Jul-Aug;31(4):20-2.
A total of 103 patients with Addison's disease were examined. The task was to determine the information content of the clinical symptoms of Addison's disease in their interrelationship. The theorem of the multiplication of probability of independent events and probability of the appearance of at least one event were used. On the basis of the above mathematical method it has been established that the most informative syndromes of Addison's disease are the combination of asthenia and adynamia with mass deficiency, arterial hypotension, skin pigmentation and nervous-psychic break-down. In comparing clinical and mathematical results it has been shown that a simultaneous appearance of the signs of the dyspeptic syndrome, its combinations with the pain abdominal syndrome and mass deficiency point out to a possibility of the Addisonian crisis or the onset of its development. At least one of three signs of muscular or articular involvement is predicted in each patient with Addison's disease. A table given in the paper makes it possible to determine the information content of numerous complexes of symptoms of Addison's disease.
共对103例艾迪生病患者进行了检查。任务是确定艾迪生病临床症状之间相互关系中的信息含量。使用了独立事件概率乘法定理和至少一个事件出现的概率。基于上述数学方法已确定，艾迪生病最具信息性的综合征是无力和动力缺乏与体重减轻、动脉低血压、皮肤色素沉着及神经精神障碍的组合。在比较临床和数学结果时发现，消化不良综合征的体征同时出现、其与腹痛综合征及体重减轻的组合提示有艾迪生病危象或其发展开始的可能性。每例艾迪生病患者预计至少会出现肌肉或关节受累的三个体征中的一个。论文中给出的表格能够确定艾迪生病众多症状组合的信息含量。
