Cowden Richard G, Chen Zhuo Job, Wilkinson Renae, Weziak-Bialowolska Dorota, Breedlove Thomas, Gundersen Craig, Shiba Koichiro, Padgett R Noah, Johnson Byron R, VanderWeele Tyler J
Human Flourishing Program, Institute for Quantitative Social Science, Harvard University, Cambridge, MA, USA.
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Commun Med (Lond). 2025 Jun 6;5(1):217. doi: 10.1038/s43856-025-00913-8.
Evidence suggests that suffering may degrade health and well-being. However, further research is needed to identify potential targets for addressing population-level suffering.
This cross-sectional study used nationally representative data from 22 countries in Wave 1 of the Global Flourishing Study (N = 202,898) to explore associations of 13 individual characteristics and retrospectively recalled childhood factors with suffering in adulthood. We conducted a modified Poisson regression by country in which suffering was regressed on all candidate predictors. Random effects meta-analyses were used to aggregate results for the 11 predictors that were common across all countries.
Our meta-analytic results suggest that a combination of risk and protective factors during childhood may be associated with suffering in adulthood. Individuals whose parents were married (versus divorced) at age 12, had a very good/somewhat good paternal relationship (versus very bad/somewhat bad) when growing up, had excellent health (versus good) when growing up, and who reported their family lived comfortably (versus got by) financially when growing up are less likely to experience suffering in adulthood, whereas those who were abused during childhood (versus not), felt like an outsider in their family when growing up (versus not), attended religious services 1-3 times a month (versus never) around age 12, and are female (versus male) have a higher likelihood of suffering in adulthood. Associations are somewhat heterogeneous across the countries.
Childhood experiences, influences, and conditions may impact experiences of suffering in adulthood. Targeted early-life interventions could mitigate the burden of suffering later in life.
有证据表明,痛苦可能会损害健康和幸福。然而,需要进一步研究以确定应对人群层面痛苦的潜在目标。
这项横断面研究使用了全球繁荣研究第1波中来自22个国家的具有全国代表性的数据(N = 202,898),以探讨13种个体特征和回顾性回忆的童年因素与成年期痛苦之间的关联。我们按国家进行了修正的泊松回归,将痛苦作为所有候选预测因素的回归变量。使用随机效应荟萃分析汇总所有国家共有的11个预测因素的结果。
我们的荟萃分析结果表明,童年时期的风险因素和保护因素相结合可能与成年期的痛苦有关。父母在其12岁时已婚(而非离婚)、成长过程中与父亲关系非常好/较好(而非非常差/较差)、成长过程中健康状况极佳(而非良好)以及报告其家庭在成长过程中经济上生活舒适(而非勉强维持)的个体在成年期经历痛苦的可能性较小,而童年时期遭受虐待(而非未遭受虐待)、成长过程中感觉自己在家庭中像个局外人(而非没有这种感觉)、在12岁左右每月参加1 - 3次宗教仪式(而非从不参加)以及为女性(而非男性)的个体在成年期遭受痛苦的可能性更高。各国之间的关联存在一定异质性。
童年经历、影响和状况可能会影响成年期的痛苦经历。有针对性的早期干预可以减轻晚年的痛苦负担。