Junker Theresa, Stage Nina, Thorlund Mie Gaedt, Rasmussen Benjamin Schnack Brandt, Mussmann Bo Redder, Nielsen Tommy Kjærgaard, Johansen Jakob Kjersgaard, Graumann Ole
Research and Innovation Unit of Radiology - UNIFY, University of Southern Denmark, Odense, Denmark.
Department of Urology, Odense University Hospital (OUH), Odense, Denmark.
Cardiovasc Intervent Radiol. 2025 Jun 6. doi: 10.1007/s00270-025-04079-7.
General anesthesia (GA) is often used during CT-guided percutaneous cryoablation (PCA) of renal tumors. This retrospective study compared GA to conscious sedation (CS), with dexmedetomidine and remifentanil, regarding theater time and hospital stay during PCA of renal tumors.
This retrospective study reviewed 350 patients treated with PCA between January 1, 2015, and December 31, 2019. Associations were analyzed between the type of anesthesia and theater time, hospital stay, complications, and clinical outcomes.
The cohort consisted of 148 patients who received PCA in GA (mean age 64.7 ± 13.4 years; 99 men) and 202 patients who received PCA in CS (mean age 66.7 ± 10.7 years; 142 men). Patients in the GA group had significantly longer theater times (mean 2.6 h ± 0.48) compared to their CS counterparts (mean 2.1 h ± 0.46; p < 0.001). Furthermore, the median length of hospital stay was significantly longer in the GA group (8.5 vs. 5.5 h, p < 0.001). In addition, patients in the GA group had significantly lower levels of consciousness in the recovery room compared to the CS group (p = 0.047). There were no differences between the groups regarding complications, graded on the CIRSE classification system (p = 0.463), or rate of incomplete ablation at three-month follow-up (p = 0.229).
Patients who undergo PCA of renal tumors under CS have significantly shorter theater time and length of hospital stay compared to patients who undergo PCA in GA, with no impact on complications or technical failure rate.
3, a retrospective cohort study.
全身麻醉(GA)常用于CT引导下肾肿瘤经皮冷冻消融术(PCA)。本回顾性研究比较了GA与使用右美托咪定和瑞芬太尼的清醒镇静(CS)在肾肿瘤PCA期间的手术时间和住院时间。
本回顾性研究对2015年1月1日至2019年12月31日期间接受PCA治疗的350例患者进行了回顾。分析了麻醉类型与手术时间、住院时间、并发症及临床结局之间的关联。
该队列包括148例接受GA下PCA的患者(平均年龄64.7±13.4岁;99例男性)和202例接受CS下PCA的患者(平均年龄66.7±10.7岁;142例男性)。与CS组患者(平均2.1 h±0.46)相比,GA组患者的手术时间明显更长(平均2.6 h±0.48;p<0.001)。此外,GA组的中位住院时间明显更长(8.5小时对5.5小时,p<0.001)。此外,与CS组相比,GA组患者在恢复室的意识水平明显较低(p=0.047)。在根据CIRSE分类系统分级的并发症方面(p=0.463),或在三个月随访时的不完全消融率方面(p=0.229),两组之间没有差异。
与接受GA下PCA的患者相比,接受CS下肾肿瘤PCA的患者的手术时间和住院时间明显更短,且对并发症或技术失败率无影响。
3,一项回顾性队列研究。