Kanda Hirotsugu, Takahashi Yukako, Sugawara Ami, Takahoko Kenichi, Shirasaka Tomonori, Saijo Yasuaki, Kamiya Hiroyuki
Department of Anesthesiology and Critical Care Medicine, Asahikawa Medical University, Asahikawa, Japan.
Department of Anesthesiology and Critical Care Medicine, Asahikawa Medical University, Asahikawa, Japan.
J Cardiothorac Vasc Anesth. 2022 Feb;36(2):452-460. doi: 10.1053/j.jvca.2021.07.005. Epub 2021 Jul 8.
The aims of the present study were to evaluate and compare the safety and feasibility, including hospitalization, intensive care unit (ICU) stay, frequency of conversion to general anesthesia (GA), pH, PaCO, and PaO, of selected patients who underwent minimally invasive mitral valve surgery (MIMVS) via a right minithoracotomy under conscious sedation (CS) to avoid GA. The authors also aimed to evaluate the perioperative management of spontaneous breathing.
A retrospective, observational study.
Single-center.
This study enrolled 101 patients who underwent MIMVS under CS or GA.
The patients who underwent MIMVS were managed under CS or GA according to indication criteria.
ICU stay (p = 0.010), postoperative time until first fluid intake (p < 0.0001), and duration of mechanical ventilation (p = 0.004) were shorter in the CS group than in the GA group. No patients converted to GA from CS. PaCO during cardiopulmonary bypass (CPB) in the CS group was significantly lower than that in the GA group. However, PaCO at the termination of CPB in the CS group was significantly higher than that in the GA group.
In the CS group, advanced-age patients with comorbidities underwent mitral surgery without postoperative complications. The authors' findings suggested that MIMVS under CS could be a potentially less-invasive method, providing a quicker recovery than MIMVS under GA.
本研究的目的是评估和比较在清醒镇静(CS)下经右胸小切口进行微创二尖瓣手术(MIMVS)以避免全身麻醉(GA)的特定患者的安全性和可行性,包括住院情况、重症监护病房(ICU)停留时间、转为全身麻醉的频率、pH值、动脉血二氧化碳分压(PaCO₂)和动脉血氧分压(PaO₂)。作者还旨在评估自主呼吸的围手术期管理。
一项回顾性观察研究。
单中心。
本研究纳入了101例行CS或GA下MIMVS的患者。
行MIMVS的患者根据适应证标准接受CS或GA管理。
CS组的ICU停留时间(p = 0.010)、术后首次进食时间(p < 0.0001)和机械通气时间(p = 0.004)均短于GA组。没有患者从CS转为GA。CS组体外循环(CPB)期间的PaCO₂显著低于GA组。然而,CS组CPB结束时的PaCO₂显著高于GA组。
在CS组中,患有合并症的老年患者接受二尖瓣手术且无术后并发症。作者的研究结果表明,CS下的MIMVS可能是一种侵入性较小的方法,比GA下的MIMVS恢复更快。