Marena Francesco, Brambullo Tito, Montrasio Lorenzo, Baldan Nicola, Mancini Francesca, Vindigni Vincenzo, Bassetto Franco
Clinic of Plastic Surgery, Department of Neurosciences, University of Padua, Address Via Giustiniani 2, Padua, Veneto, Italy.
1 st Surgical Clinic, Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.
Eur J Med Res. 2025 Jun 7;30(1):464. doi: 10.1186/s40001-025-02724-y.
A single-center retrospective study was conducted to investigate whether the prophylactic application of a single-use negative pressure wound therapy (sNPWT) dressing on closed surgical incisions following incisional hernia (IH) repair of the abdominal wall with meshes reduces the risk of surgical site occurrence (SSO) and the necessity for surgical reoperation.
A retrospective study was conducted on 55 patients with incisional hernias classified as W2 (> 4-10 cm) or W3 (> 10 cm) according to the European Hernia Society classification, treated between 2013 and 2023. All patients underwent open surgical repair with mesh and were assigned to either a conventional flat dressing group (n = 34) or an sNPWT group using PICO 7 (n = 21). Weekly follow-ups were performed, and outcomes were statistically analyzed to compare the incidence of SSOs and reoperations between the two groups.
At 30 days postoperatively, the control group showed a higher incidence of SSOs (32.35%, 11 cases) compared to the PICO 7 group (19.05%, 4 cases, P = 0.28). The need for surgical reintervention was also higher in the control group (17.65%, 6 cases) versus the PICO 7 group (10.53%, 2 cases, P = 0.41). Regardless of dressing type, elevated BMI (P = 0.02), advanced age, and diabetes were identified as key risk factors for SSOs.
sNPWT with PICO 7 may reduce SSOs and reoperations in open incisional hernia repair, particularly in high-risk patients with elevated BMI. Although statistical significance was not achieved, sNPWT appears to be a valuable adjunct in postoperative management. Further research is necessary to confirm its efficacy and determine the ideal patient population.
开展了一项单中心回顾性研究，以调查在使用补片进行腹壁切口疝（IH）修补术后的闭合手术切口中预防性应用一次性负压伤口治疗（sNPWT）敷料是否能降低手术部位事件（SSO）的风险以及再次手术的必要性。
对2013年至2023年间治疗的55例根据欧洲疝学会分类法分类为W2（>4 - 10厘米）或W3（>10厘米）的切口疝患者进行回顾性研究。所有患者均接受了补片开放手术修补，并被分配至传统扁平敷料组（n = 34）或使用PICO 7的sNPWT组（n = 21）。每周进行随访，并对结果进行统计分析，以比较两组之间SSO和再次手术的发生率。
术后30天时，对照组的SSO发生率（32.35%，11例）高于PICO 7组（19.05%，4例，P = 0.28）。对照组的手术再次干预需求（17.65%，6例）也高于PICO 7组（10.53%，2例，P = 0.41）。无论敷料类型如何，BMI升高（P = 0.02）、高龄和糖尿病被确定为SSO的关键风险因素。
使用PICO 7的sNPWT可能会降低开放切口疝修补术中的SSO和再次手术率，尤其是在BMI升高的高危患者中。尽管未达到统计学显著性，但sNPWT似乎是术后管理中有价值的辅助手段。有必要进一步研究以证实其疗效并确定理想的患者群体。
