含固体分散体颗粒的压制。
The compression of granulates containing solid dispersions.
作者信息
Kinget R, Kemel R
出版信息
Pharmazie. 1985 Jul;40(7):475-7.
PMID:4048252
Abstract
In the present work granulates containing solid dispersions of diazepam were compressed into tablets. The results show that polyethyleneglycol (PEG 6000) give the best tablets which disintegrate when a strong disintegrant is added extragranularly. The tablets keep their good physical properties when stored in normal or low humidity conditions.
摘要
在本研究中，将含有地西泮固体分散体的颗粒压制成片剂。结果表明，聚乙二醇（PEG 6000）制成的片剂最佳，当在颗粒外添加强崩解剂时片剂会崩解。在正常或低湿度条件下储存时，这些片剂保持其良好的物理性质。
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