Pentland B, Mitchell J D, Cull R E, Ford M J
Q J Med. 1985 Aug;56(220):457-65.
The presenting features, clinical course and outcome of 19 patients with a diagnosis of CNS sarcoidosis are described. In two-thirds of the patients the initial features of sarcoidosis were neurological; half of them had an acute monophasic illness and half a chronic progressive or relapsing course. A favourable outcome was recorded unexpectedly during a study period of one to 16 years for two-thirds of the patients. The course of the disease in four patients suggested multiple sclerosis thus emphasising the importance of considering the possibility of CNS sarcoidosis in patients with suspected demyelinating disease.
本文描述了19例经诊断为中枢神经系统结节病患者的临床表现、临床病程及预后。三分之二的患者结节病的首发症状为神经系统症状；其中一半患者呈急性单相病程，另一半患者呈慢性进行性或复发病程。在1至16年的研究期间，三分之二的患者意外地获得了良好的预后。4例患者的病程提示为多发性硬化，这凸显了在疑似脱髓鞘疾病患者中考虑中枢神经系统结节病可能性的重要性。
